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Invitrogen
Carboxypeptidase B2 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (11A4)
产品信息
MA5-54538
产品规格
种属反应
Human
宿主/亚型
Alpaca
/ VHH
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
11A4
抗原
Recombinant Human CPB2/TAFI.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Metal-chelate chromatography
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
产品详细信息
Compatible with Direct ELISA
靶标信息
Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for its gene and its promoter region.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: carboxypeptidase B-like protein; Carboxypeptidase B2; carboxypeptidase B2 (plasma); carboxypeptidase B2 (plasma, carboxypeptidase U); carboxypeptidase R; Carboxypeptidase U; CPU; pCPB; Plasma carboxypeptidase B; TAFI; Thrombin-activable fibrinolysis inhibitor; thrombin-activatable fibrinolysis inhibitor
基因别名: CPB2; CPU; PCPB; TAFI
UniProt ID: (Human) Q96IY4
Entrez Gene ID: (Human) 1361
positive regulation of extracellular matrix constituent secretion
proteolysis
blood coagulation
response to heat
negative regulation of plasminogen activation
response to drug
fibrinolysis
negative regulation of fibrinolysis
cellular response to glucose stimulus
liver regeneration
negative regulation of hepatocyte proliferation
