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Carboxypeptidase E Antibody (PA5-28376) in IHC (P)
Carboxypeptidase E Polyclonal Antibody detects Carboxypeptidase E protein at nucleus on human breast cancer by immunohistochemical analysis. Sample: Paraffin-embedded breast cancer. Carboxypeptidase E Polyclonal Antibody (Product # PA5-28376) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
产品信息
PA5-28376
产品规格
种属反应
Human,
Mouse
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 143 and 388 of Human Carboxypeptidase E
偶联物
形式
Liquid
浓度
0.68 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2545852
产品详细信息
Recommended positive controls: Carboxypeptidase H tansfected 293T cell, mouse brain.
Predicted reactivity: Mouse (96%), Rat (96%), Zebrafish (85%), Xenopus laevis (83%), Pig (95%), Rhesus Monkey (99%), Chimpanzee (99%), Bovine (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Carboxypeptidase E; Carboxypeptidase H; CarboxypeptidaseE; CarboxypeptidaseH; CBPE; cobalt-stimulated chromaffin granule carboxypeptidase; CPE; CPH; Cph 1; Enkephalin convertase; insulin granule-associated carboxypeptidase; Prohormone-processing carboxypeptidase
基因别名: CPE; CPH; Cph-1; Cph1; fat; R74677
UniProt ID: (Human) P16870, (Mouse) Q00493
Entrez Gene ID: (Human) 1363, (Mouse) 12876
carboxypeptidase activity
metallocarboxypeptidase activity
serine-type carboxypeptidase activity
zinc ion binding
neurexin family protein binding
cell adhesion molecule binding
peptidase activity
metallopeptidase activity
hydrolase activity
protein domain specific binding
metal ion binding
cobalt ion binding
protease
cardiac left ventricle morphogenesis
cellular protein modification process
neuropeptide signaling pathway
metabolic process
Wnt signaling pathway
insulin processing
protein localization to membrane
proteolysis
peptide metabolic process
protein processing
enkephalin processing
peptide catabolic process
negative regulation of branching morphogenesis of a nerve
