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Carboxypeptidase E Antibody (PA5-47514) in ICC/IF
Immunocytochemistry analysis of Carboxypeptidase E in immersion fixed HepG2 human hepatocellular carcinoma cell line. Samples were incubated in Carboxypeptidase E polyclonal antibody (Product # PA5-47514) using a dilution of 10 µg/mL for 3 hours at room temperature followed by NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red, upper panel) and counterstained with DAPI (blue, lower panel).... View More
产品信息
PA5-47514
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant human Carboxypeptidase E/CPE Arg42-Ser453
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2609354
产品详细信息
In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human (rh) CPA1, recombinant mouse CPA4 and rhCPB1 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
This gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Carboxypeptidase E; Carboxypeptidase H; CarboxypeptidaseE; CarboxypeptidaseH; CBPE; cobalt-stimulated chromaffin granule carboxypeptidase; CPE; CPH; Cph 1; Enkephalin convertase; insulin granule-associated carboxypeptidase; Prohormone-processing carboxypeptidase
基因别名: CPE; CPH
UniProt ID: (Human) P16870
Entrez Gene ID: (Human) 1363
