Product References
Genipin prevents alpha-synuclein aggregation and toxicity by affecting endocytosis, metabolism and lipid storage.
Nature communications
Rosado-Ramos R,Poças GM,Marques D,Foito A,M Sevillano D,Lopes-da-Silva M,Gonçalves LG,Menezes R,Ottens M,Stewart D,Ibáñez de Opakua A,Zweckstetter M,Seabra MC,Mendes CS,Outeiro TF,Domingos PM,Santos CN
A-6428 was used in Western Blotting to identify genipin, an iridoid, which relieves αSyn toxicity and aggregation.
Thu Apr 06 00:00:00 UTC 2023
Genipin prevents alpha-synuclein aggregation and toxicity by affecting endocytosis, metabolism and lipid storage.
Nature communications
Rosado-Ramos R,Poças GM,Marques D,Foito A,M Sevillano D,Lopes-da-Silva M,Gonçalves LG,Menezes R,Ottens M,Stewart D,Ibáñez de Opakua A,Zweckstetter M,Seabra MC,Mendes CS,Outeiro TF,Domingos PM,Santos CN
A-6428 was used in Western Blotting to identify genipin, an iridoid, which relieves αSyn toxicity and aggregation.
Thu Apr 06 00:00:00 UTC 2023
A two-tiered system for selective receptor and transporter protein degradation.
PLoS genetics
Golden CK,Kazmirchuk TDD,McNally EK,El Eissawi M,Gokbayrak ZD,Richard JD,Brett CL
A-6428 was used in Immunocytochemistry, Western Blot, Sample Prep to study the adaptive mechanisms involved with loss-of-function mutations in human ESCRT genes and homologous mutations.
Sat Oct 01 00:00:00 UTC 2022
Fumarase affects the deoxyribonucleic acid damage response by protecting the mitochondrial desulfurase Nfs1p from modification and inactivation.
iScience
Yip J,Wang S,Tan J,Lim TK,Lin Q,Yu Z,Karmon O,Pines O,Lehming N
A-6428 was used in Western Blot to show that the overexpression of the cysteine desulfurase Nfs1p restores DNA repair in fumarase-deficient yeast cells.
Fri Nov 19 00:00:00 UTC 2021
Fumarase affects the deoxyribonucleic acid damage response by protecting the mitochondrial desulfurase Nfs1p from modification and inactivation.
iScience
Yip J,Wang S,Tan J,Lim TK,Lin Q,Yu Z,Karmon O,Pines O,Lehming N
A-6428 was used in Western Blot to show that the overexpression of the cysteine desulfurase Nfs1p restores DNA repair in fumarase-deficient yeast cells.
Fri Nov 19 00:00:00 UTC 2021
A conserved ATG2 binding site in WIPI4 and yeast Hsv2 is disrupted by mutations causing β-propeller protein-associated neurodegeneration.
Human molecular genetics
Bueno-Arribas M,Blanca I,Cruz-Cuevas C,Escalante R,Navas MA,Vincent O
A-6428 was used in Western Blotting to show that the Atg2 binding site is conserved in Hsv2 and WIPI4 but not in Atg18.
Fri Dec 17 00:00:00 UTC 2021
Cysteine Toxicity Drives Age-Related Mitochondrial Decline by Altering Iron Homeostasis.
Cell
Hughes CE,Coody TK,Jeong MY,Berg JA,Winge DR,Hughes AL
A-6428 was used in Western Blotting to demonstrate that cysteine toxicity is a major driver of age-related mitochondrial deterioration and identify vacuolar amino acid compartmentation as a cellular strategy to minimize amino acid toxicity.
Thu Jan 23 00:00:00 UTC 2020
A Cycle of Ubiquitination Regulates Adaptor Function of the Nedd4-Family Ubiquitin Ligase Rsp5.
Current biology : CB
MacDonald C,Shields SB,Williams CA,Winistorfer S,Piper RC
A-6428 was used in Western Blotting to support a model whereby ubiquitinated Rsp5 adaptors are more active when "locked" onto Rsp5 via its N-lobe ubiquitin-binding surface and less active when they are "unlocked" by Ubp2-mediated deubiquitination.
Mon Feb 03 00:00:00 UTC 2020
Nuclear envelope-vacuole contacts mitigate nuclear pore complex assembly stress.
The Journal of cell biology
Lord CL,Wente SR
A-6428 was used in Western Blot to define how NE-vacuole interorganelle contacts coordinate responses to mitigate deleterious cellular effects caused by disrupted NPC assembly.
Mon Dec 07 00:00:00 UTC 2020
Nuclear envelope-vacuole contacts mitigate nuclear pore complex assembly stress.
The Journal of cell biology
Lord CL,Wente SR
A-6428 was used in Western Blot to define how NE-vacuole interorganelle contacts coordinate responses to mitigate deleterious cellular effects caused by disrupted NPC assembly.
Mon Dec 07 00:00:00 UTC 2020
Mammalian Retromer Is an Adaptable Scaffold for Cargo Sorting from Endosomes.
Structure (London, England : 1993)
Kendall AK,Xie B,Xu P,Wang J,Burcham R,Frazier MN,Binshtein E,Wei H,Graham TR,Nakagawa T,Jackson LP
A-6428 was used in Western Blotting to uncover the multiple structures of oligomer associated with metazoan retromer (VPS26/VPS35/VPS29) using the combination of single-particle cryoelectron microscopy and biophysical methods.f.
Tue Apr 07 00:00:00 UTC 2020
A VPS13D spastic ataxia mutation disrupts the conserved adaptor-binding site in yeast Vps13.
Human molecular genetics
Dziurdzik SK,Bean BDM,Davey M,Conibear E
Published figure using Carboxypeptidase Y monoclonal antibody (Product # A-6428) in Dot blot
Fri Mar 13 00:00:00 UTC 2020
Chromatographic detection of low-molecular-mass metal complexes in the cytosol of Saccharomyces cerevisiae.
Metallomics : integrated biometal science
Nguyen TQ,Kim JE,Brawley HN,Lindahl PA
A-6428 was used in Western Blotting to use chromatography to directly detect labile low-molecular-mass (LMM) metal pools in the cytosol of eukaryotic cells.
Wed Jul 01 00:00:00 UTC 2020
Chromatographic detection of low-molecular-mass metal complexes in the cytosol of Saccharomyces cerevisiae.
Metallomics : integrated biometal science
Nguyen TQ,Kim JE,Brawley HN,Lindahl PA
A-6428 was used in Western Blotting to use chromatography to directly detect labile low-molecular-mass (LMM) metal pools in the cytosol of eukaryotic cells.
Wed Jul 01 00:00:00 UTC 2020
Gyp1 has a dual function as Ypt1 GAP and interaction partner of Atg8 in selective autophagy.
Autophagy
Mitter AL,Schlotterhose P,Krick R
A-6428 was used in Western Blotting to investigate the molecular mechanisms of Ypt1-Atg1 complex disassembly during phagophore formation.
Sat Jun 01 00:00:00 UTC 2019
Isolated Saccharomyces cerevisiae vacuoles contain low-molecular-mass transition-metal polyphosphate complexes.
Metallomics : integrated biometal science
Nguyen TQ,Dziuba N,Lindahl PA
A-6428 was used in Western Blotting to indicate metal:polyphosphate complexes 6-20 phosphate units in length and coordinated by 1-3 metals on average per chain.
Wed Jul 17 00:00:00 UTC 2019
Rsp5 and Mdm30 reshape the mitochondrial network in response to age-induced vacuole stress.
Molecular biology of the cell
Goodrum JM,Lever AR,Coody TK,Gottschling DE,Hughes AL
A-6428 was used in Western Blotting to study the molecular pathways involved in the stress-responsive regulation of mitochondrial structure.
Thu Aug 01 00:00:00 UTC 2019
Inhibiting Stearoyl-CoA Desaturase Ameliorates α-Synuclein Cytotoxicity.
Cell reports
Vincent BM,Tardiff DF,Piotrowski JS,Aron R,Lucas MC,Chung CY,Bacherman H,Chen Y,Pires M,Subramaniam R,Doshi DB,Sadlish H,Raja WK,Solís EJ,Khurana V,Le Bourdonnec B,Scannevin RH,Rhodes KJ
A-6428 was used in Western Blotting to identify a new therapeutic target for diseases caused by α-synuclein, a small lipid-binding protein that misfolds and aggregates in Parkinson's disease and other disorders.
Tue Dec 04 00:00:00 UTC 2018
Failure of RQC machinery causes protein aggregation and proteotoxic stress.
Nature
Choe YJ,Park SH,Hassemer T,Körner R,Vincenz-Donnelly L,Hayer-Hartl M,Hartl FU
A-6428 was used in Immunoprecipitation, Immunocytochemistry, Western Blot to show that deletion of the E3 ubiquitin ligase Ltn1p in yeast, a key RQC component, causes stalled proteins to form detergent-resistant aggregates and inclusions.
Thu Mar 10 00:00:00 UTC 2016
An Analog-sensitive Version of the Protein Kinase Slt2 Allows Identification of Novel Targets of the Yeast Cell Wall Integrity Pathway.
The Journal of biological chemistry
Alonso-Rodríguez E,Fernández-Piñar P,Sacristán-Reviriego A,Molina M,Martín H
A-6428 was used in Western Blotting to identify novel targets of the yeast cell wall integrity MAPK, Slt2, using an analogue-sensitive mutant.
Fri Mar 11 00:00:00 UTC 2016
An Analog-sensitive Version of the Protein Kinase Slt2 Allows Identification of Novel Targets of the Yeast Cell Wall Integrity Pathway.
The Journal of biological chemistry
Alonso-Rodríguez E,Fernández-Piñar P,Sacristán-Reviriego A,Molina M,Martín H
A-6428 was used in Western Blotting to identify novel targets of the yeast cell wall integrity MAPK, Slt2, using an analogue-sensitive mutant.
Fri Mar 11 00:00:00 UTC 2016
A Complex of Htm1 and the Oxidoreductase Pdi1 Accelerates Degradation of Misfolded Glycoproteins.
The Journal of biological chemistry
Pfeiffer A,Stephanowitz H,Krause E,Volkwein C,Hirsch C,Jarosch E,Sommer T
A-6428 was used in western blot to study acceleration of degradation of misfolded glycoproteins by a complex of Htm1 and the oxidoreductase Pdi1
Fri Jun 03 00:00:00 UTC 2016
Functions of Ceramide Synthase Paralogs YPR114w and YJR116w of Saccharomyces cerevisiae.
PloS one
Mallela SK,Almeida R,Ejsing CS,Conzelmann A
A-6428 was used in western blot to test function of ceramide syntase paralogs YJR116w and YPR114w of Saccharomyces cerevisiae
Thu Jun 30 00:00:00 UTC 2016
Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes.
Science (New York, N.Y.)
Rostislavleva K,Soler N,Ohashi Y,Zhang L,Pardon E,Burke JE,Masson GR,Johnson C,Steyaert J,Ktistakis NT,Williams RL
A-6428 was used in immunocytochemistry to report the crystal structure of the 385-kilodalton endosomal complex II.
Fri Oct 09 00:00:00 UTC 2015
The coordinated action of the MVB pathway and autophagy ensures cell survival during starvation.
eLife
Müller M,Schmidt O,Angelova M,Faserl K,Weys S,Kremser L,Pfaffenwimmer T,Dalik T,Kraft C,Trajanoski Z,Lindner H,Teis D
A-6428 was used in western blot to study the interaction between the MVB pathway and autophagy ensures cell survival during starvation
Wed Apr 22 00:00:00 UTC 2015
Arabidopsis DOK1 encodes a functional dolichol kinase involved in reproduction.
The Plant journal : for cell and molecular biology
Kanehara K,Cho Y,Lin YC,Chen CE,Yu CY,Nakamura Y
Published figure using Carboxypeptidase Y monoclonal antibody (Product # A-6428) in Western Blot
Thu Jan 01 00:00:00 UTC 2015
Rab5-family guanine nucleotide exchange factors bind retromer and promote its recruitment to endosomes.
Molecular biology of the cell
Bean BD,Davey M,Snider J,Jessulat M,Deineko V,Tinney M,Stagljar I,Babu M,Conibear E
Published figure using Carboxypeptidase Y monoclonal antibody (Product # A-6428) in Western Blot
Sun Mar 15 00:00:00 UTC 2015
POLYPRENOL REDUCTASE2 Deficiency Is Lethal in Arabidopsis Due to Male Sterility.
The Plant cell
Jozwiak A,Gutkowska M,Gawarecka K,Surmacz L,Buczkowska A,Lichocka M,Nowakowska J,Swiezewska E
A-6428 was used in Western Blotting to elucidate the factors mediating the key step of the dolichol cycle in plant cells which makes manipulation of dolichol content in plant tissues feasible.
Tue Dec 01 00:00:00 UTC 2015
Yeast reveal a "druggable" Rsp5/Nedd4 network that ameliorates α-synuclein toxicity in neurons.
Science (New York, N.Y.)
Tardiff DF,Jui NT,Khurana V,Tambe MA,Thompson ML,Chung CY,Kamadurai HB,Kim HT,Lancaster AK,Caldwell KA,Caldwell GA,Rochet JC,Buchwald SL,Lindquist S
Published figure using Carboxypeptidase Y monoclonal antibody (Product # A-6428) in Western Blot
Fri Nov 22 00:00:00 UTC 2013
Golgi-mediated glycosylation determines residency of the T2 RNase Rny1p in Saccharomyces cerevisiae.
Traffic (Copenhagen, Denmark)
Shcherbik N
A-6428 was used in Western Blotting to study how glycosylation affects the progression of the T2 RNase Rny1p through the secretory pathway in Sacchromyces cerevisiae.
Sun Dec 01 00:00:00 UTC 2013
Topology, glycosylation and conformational changes in the membrane domain of the vacuolar H+-ATPase a subunit.
Journal of cellular biochemistry
Kartner N,Yao Y,Bhargava A,Manolson MF
A-6428 was used in western blot to construct and experimentally test a predictive model of the membrane insertion of the yeast a subunit, Vph1p.
Mon Jul 01 00:00:00 UTC 2013
Regulation of cell wall synthesis by the clathrin light chain is essential for viability in Schizosaccharomyces pombe.
PloS one
de León N,Sharifmoghadam MR,Hoya M,Curto MÁ,Doncel C,Valdivieso MH
A-6428 was used in western blot to study the regulation of cell wall synthesis by the clathrin light chain.
Tue Apr 08 00:00:00 UTC 2014
A role for Atg8-PE deconjugation in autophagosome biogenesis.
Autophagy
Nair U,Yen WL,Mari M,Cao Y,Xie Z,Baba M,Reggiori F,Klionsky DJ
Published figure using Carboxypeptidase Y monoclonal antibody (Product # A-6428) in Western Blot
Tue May 01 00:00:00 UTC 2012
Plant-specific cation/H+ exchanger 17 and its homologs are endomembrane K+ transporters with roles in protein sorting.
The Journal of biological chemistry
Chanroj S,Lu Y,Padmanaban S,Nanatani K,Uozumi N,Rao R,Sze H
A-6428 was used in ELISA to examine how CHX transporters differentially modulate K(+) and pH homeostasis of distinct intracellular compartments.
Fri Sep 30 00:00:00 UTC 2011
Plant-specific cation/H+ exchanger 17 and its homologs are endomembrane K+ transporters with roles in protein sorting.
The Journal of biological chemistry
Chanroj S,Lu Y,Padmanaban S,Nanatani K,Uozumi N,Rao R,Sze H
A-6428 was used in ELISA to examine how CHX transporters differentially modulate K(+) and pH homeostasis of distinct intracellular compartments.
Fri Sep 30 00:00:00 UTC 2011
A conserved coatomer-related complex containing Sec13 and Seh1 dynamically associates with the vacuole in Saccharomyces cerevisiae.
Molecular & cellular proteomics : MCP
Dokudovskaya S,Waharte F,Schlessinger A,Pieper U,Devos DP,Cristea IM,Williams R,Salamero J,Chait BT,Sali A,Field MC,Rout MP,Dargemont C
A-6428 was used in western blot to identify the SEA complex is a member of a family of membrane coating and vesicle tethering assemblies needed for intracellular trafficking, amino acid biogenesis, and response to nitrogen starvation.
Wed Jun 01 00:00:00 UTC 2011
SRD5A3 is required for converting polyprenol to dolichol and is mutated in a congenital glycosylation disorder.
Cell
Cantagrel V,Lefeber DJ,Ng BG,Guan Z,Silhavy JL,Bielas SL,Lehle L,Hombauer H,Adamowicz M,Swiezewska E,De Brouwer AP,Blümel P,Sykut-Cegielska J,Houliston S,Swistun D,Ali BR,Dobyns WB,Babovic-Vuksanovic D,van Bokhoven H,Wevers RA,Raetz CR,Freeze HH,Morava E,Al-Gazali L,Gleeson JG
A-6428 was used in western blot to identify a new type of congenital disorder of glycosylation caused by steroid 5alpha-reductase type 3 mutations
Fri Jul 23 00:00:00 UTC 2010
A plasma-membrane E-MAP reveals links of the eisosome with sphingolipid metabolism and endosomal trafficking.
Nature structural & molecular biology
Aguilar PS,Fröhlich F,Rehman M,Shales M,Ulitsky I,Olivera-Couto A,Braberg H,Shamir R,Walter P,Mann M,Ejsing CS,Krogan NJ,Walther TC
A-6428 was used in western blot to use a quantitative genetic interaction map to study plasma membrane biology
Thu Jul 01 00:00:00 UTC 2010
Proteolytic instability and the action of nonclassical transcriptional activators.
Current biology : CB
Wang X,Muratani M,Tansey WP,Ptashne M
A-6428 was used in western blot to study yeast activators
Tue May 11 00:00:00 UTC 2010
Genome-wide analysis of membrane transport using yeast knockout arrays.
Methods in molecular biology (Clifton, N.J.)
Burston HE,Davey M,Conibear E
A-6428 was used in Flow Cytometry to identify novel transport genes using yeast knockout arrays.
Tue Jan 06 00:00:00 UTC 2009
Grd19/Snx3p functions as a cargo-specific adapter for retromer-dependent endocytic recycling.
The Journal of cell biology
Strochlic TI,Setty TG,Sitaram A,Burd CG
A-6428 was used in western blot to study the endocytic sorting of the yeast reductive iron transporter
Mon Apr 09 00:00:00 UTC 2007
A complex of Yos9p and the HRD ligase integrates endoplasmic reticulum quality control into the degradation machinery.
Nature cell biology
Gauss R,Jarosch E,Sommer T,Hirsch C
A-6428 was used in immunoprecipitation and western blot to investigate the association between Yos9p and Hrd3p
Tue Aug 01 00:00:00 UTC 2006
A screen for genes of heme uptake identifies the FLC family required for import of FAD into the endoplasmic reticulum.
The Journal of biological chemistry
Protchenko O,Rodriguez-Suarez R,Androphy R,Bussey H,Philpott CC
A-6428 was used in immunoprecipitation to identify the FLC family required for import of FAD into the endoplasmic reticulum by a screen for genes of heme uptake
Fri Jul 28 00:00:00 UTC 2006
PKR1 encodes an assembly factor for the yeast V-type ATPase.
The Journal of biological chemistry
Davis-Kaplan SR,Compton MA,Flannery AR,Ward DM,Kaplan J,Stevens TH,Graham LA
A-6428 was used in western blot to study an encoded assembly factor for the yeast V-type ATPase called PKR1
Fri Oct 20 00:00:00 UTC 2006
The F box protein Dsg1/Mdm30 is a transcriptional coactivator that stimulates Gal4 turnover and cotranscriptional mRNA processing.
Cell
Muratani M,Kung C,Shokat KM,Tansey WP
A-6428 was used in western blot to study the ubiquitin-mediated proteolysis of Gal4
Fri Mar 25 00:00:00 UTC 2005
Traffic-independent function of the Sar1p/COPII machinery in proteasomal sorting of the cystic fibrosis transmembrane conductance regulator.
The Journal of cell biology
Fu L,Sztul E
A-6428 was used in immunoprecipitation to use yeast to study the relationship between sequestration and degradation of the cystic fibrosis transmembrane conductance regulator
Mon Jan 20 00:00:00 UTC 2003
Degradation of endoplasmic reticulum (ER) quality control substrates requires transport between the ER and Golgi.
The Journal of biological chemistry
Caldwell SR,Hill KJ,Cooper AA
A-6428 was used in immunoprecipitation to study the degradation and transport of endoplasmic reticulum quality control substrates
Fri Jun 29 00:00:00 UTC 2001
Sorting of yeast membrane proteins into an endosome-to-Golgi pathway involves direct interaction of their cytosolic domains with Vps35p.
The Journal of cell biology
Nothwehr SF,Ha SA,Bruinsma P
A-6428 was used in immunoprecipitation to study the role of Vps35p in transporting cargo proteins.
Mon Oct 16 00:00:00 UTC 2000
A screen for dominant negative mutants of SEC18 reveals a role for the AAA protein consensus sequence in ATP hydrolysis.
Molecular biology of the cell
Steel GJ,Harley C,Boyd A,Morgan A
A-6428 was used in western blot to elucidate the structure and function of N-ethylmaleimide-sensitive fusion protein
Sat Apr 01 00:00:00 UTC 2000
Luv1p/Rki1p/Tcs3p/Vps54p, a yeast protein that localizes to the late Golgi and early endosome, is required for normal vacuolar morphology.
Molecular biology of the cell
Conboy MJ,Cyert MS
A-6428 was used in immunocytochemistry to characterize LUV1/RKI1/TCS3/VPS54
Sat Jul 01 00:00:00 UTC 2000
Altered distribution of the yeast plasma membrane H+-ATPase as a feature of vacuolar H+-ATPase null mutants.
The Journal of biological chemistry
Perzov N,Nelson H,Nelson N
A-6428 was used in western blot to assess the effect of vacuolar H(+)-ATPase null mutations on the targeting of the plasma membrane H(+)-ATPase through the secretory pathway.
Fri Dec 22 00:00:00 UTC 2000
Altered distribution of the yeast plasma membrane H+-ATPase as a feature of vacuolar H+-ATPase null mutants.
The Journal of biological chemistry
Perzov N,Nelson H,Nelson N
A-6428 was used in western blot to assess the effect of vacuolar H(+)-ATPase null mutations on the targeting of the plasma membrane H(+)-ATPase through the secretory pathway.
Fri Dec 22 00:00:00 UTC 2000
YLL031c belongs to a novel family of membrane proteins involved in the transfer of ethanolaminephosphate onto the core structure of glycosylphosphatidylinositol anchors in yeast.
The Journal of biological chemistry
Flury I,Benachour A,Conzelmann A
A-6428 was used in western blot to test if YLL031c plays any role in glycosylphosphatidylinositol anchoring
Fri Aug 11 00:00:00 UTC 2000
Desferrioxamine-mediated iron uptake in Saccharomyces cerevisiae. Evidence for two pathways of iron uptake.
The Journal of biological chemistry
Yun CW,Ferea T,Rashford J,Ardon O,Brown PO,Botstein D,Kaplan J,Philpott CC
A-6428 was used in western blot to identify new iron and AFT1-regulated genes in yeast
Fri Apr 07 00:00:00 UTC 2000
Syntaxin 7 mediates endocytic trafficking to late endosomes.
The Journal of biological chemistry
Nakamura N,Yamamoto A,Wada Y,Futai M
A-6428 was used in western blot to investigate the role of syntaxin 7 in endocytic trafficking from early endosomes to late endosomes and lysosomes
Fri Mar 03 00:00:00 UTC 2000
Specific sterols required for the internalization step of endocytosis in yeast.
Molecular biology of the cell
Munn AL,Heese-Peck A,Stevenson BJ,Pichler H,Riezman H
A-6428 was used in immunoprecipitation and western blot to study a sterol mutant defective in the internalization step of endocytosis
Mon Nov 01 00:00:00 UTC 1999
A syntaxin homolog encoded by VAM3 mediates down-regulation of a yeast G protein-coupled receptor.
The Journal of biological chemistry
Stefan CJ,Blumer KJ
A-6428 was used in western blot to show that Vam3 is required for the delivery of alpha-factor receptor-ligand complexes to the vacuole
Fri Jan 15 00:00:00 UTC 1999
Ligand recognition and domain structure of Vps10p, a vacuolar protein sorting receptor in Saccharomyces cerevisiae.
European journal of biochemistry
Jørgensen MU,Emr SD,Winther JR
A-6428 was used in immunoprecipitation to characterize ligand binding to Vps10p
Mon Mar 01 00:00:00 UTC 1999
Substrate- and inhibitor-induced conformational changes in the yeast V-ATPase provide evidence for communication between the catalytic and proton-translocating sectors.
The Journal of biological chemistry
Landolt-Marticorena C,Kahr WH,Zawarinski P,Correa J,Manolson MF
A-6428 was used in western blot to study nucleotide- and cation- induced changes in the catalytic core of the V-ATPase
Fri Sep 10 00:00:00 UTC 1999
Der3p/Hrd1p is required for endoplasmic reticulum-associated degradation of misfolded lumenal and integral membrane proteins.
Molecular biology of the cell
Bordallo J,Plemper RK,Finger A,Wolf DH
A-6428 was used in western blot to investigate the endoplasmic reticulum proofreading and degradation system in the yeast Saccharomyces cerevisiae
Thu Jan 01 00:00:00 UTC 1998
A multispecificity syntaxin homologue, Vam3p, essential for autophagic and biosynthetic protein transport to the vacuole.
The Journal of cell biology
Darsow T,Rieder SE,Emr SD
A-6428 was used in immunoprecipitation to determine the function of Vam3p
Mon Aug 11 00:00:00 UTC 1997
Novel genes involved in endosomal traffic in yeast revealed by suppression of a targeting-defective plasma membrane ATPase mutant.
The Journal of cell biology
Luo Wj,Chang A
A-6428 was used in western blot to identify genes regulating traffic in the yeast endosomal system
Mon Aug 25 00:00:00 UTC 1997
A novel complex of nucleoporins, which includes Sec13p and a Sec13p homolog, is essential for normal nuclear pores.
Cell
Siniossoglou S,Wimmer C,Rieger M,Doye V,Tekotte H,Weise C,Emig S,Segref A,Hurt EC
A-6428 was used in western blot to screen for nucleoporin-interacting components and identify Nup84p
Fri Jan 26 00:00:00 UTC 1996
Vps10p cycles between the late-Golgi and prevacuolar compartments in its function as the sorting receptor for multiple yeast vacuolar hydrolases.
The Journal of cell biology
Cooper AA,Stevens TH
A-6428 was used in immunoprecipitation to discuss the characteristics and functions of Vacuolar Protein Sorting 10
Wed May 01 00:00:00 UTC 1996
Vacuole partitioning during meiotic division in yeast.
Genetics
Roeder AD,Shaw JM
A-6428 was used in immunocytochemistry to study partitioning of the yeast vacuole during meiotic division
Tue Oct 01 00:00:00 UTC 1996
VPS27 controls vacuolar and endocytic traffic through a prevacuolar compartment in Saccharomyces cerevisiae.
The Journal of cell biology
Piper RC,Cooper AA,Yang H,Stevens TH
A-6428 was used in immunoprecipitation to suggest that Vps27p controls membrane traffic through the prevacuolar/endosomal compartment
Wed Nov 01 00:00:00 UTC 1995
