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产品信息
PA5-17007
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues surrounding Gly320 of human cathepsin B in a region that is conserved in mouse and rat
偶联物
形式
Liquid
纯化类型
Antigen affinity chromatography
保存液
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_10977236
产品详细信息
It is not recommended to aliquot this antibody.
靶标信息
Cathepsin B is a lysosomal cysteine protease that has been implicated in the pathogenesis of rheumatoid arthritis, muscular dystrophy and tumor metastasis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: amyloid precursor protein secretase; APP secretase; APPS; Cathepsin B; Cathepsin B heavy chain; Cathepsin B light chain; Cathepsin B1; cysteine protease
基因别名: APPS; CB; CPSB; CTSB
UniProt ID: (Human) P07858, (Mouse) P10605
Entrez Gene ID: (Human) 1508, (Mouse) 13030
cysteine-type endopeptidase activity
serine-type endopeptidase activity
protein binding
collagen binding
peptidase activity
cysteine-type peptidase activity
kininogen binding
peptide binding
proteoglycan binding
protein self-association
endopeptidase activity
hydrolase activity
protein complex binding
toll-like receptor signaling pathway
proteolysis
autophagy
spermatogenesis
skeletal muscle tissue development
response to wounding
response to glucose
response to organic cyclic compound
response to amine
collagen catabolic process
epithelial cell differentiation
regulation of apoptotic process
response to peptide hormone
response to ethanol
decidualization
viral entry into host cell
regulation of catalytic activity
proteolysis involved in cellular protein catabolic process
negative regulation of cell death
response to interleukin-4
cellular response to mechanical stimulus
cellular response to thyroid hormone stimulus
