Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
PA5-87537
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 18-339 of human Cathepsin B (NP_0018991)
偶联物
形式
Liquid
浓度
1.26 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2804234
产品详细信息
Immunogen sequence: RSRPSFHPLS DELVNYVNKR NTTWQAGHNF YNVDMSYLKR LCGTFLGGPK PPQRVMFTED LKLPASFDAR EQWPQCPTIK EIRDQGSCGS CWAFGAVEAI SDRICIHTNA HVSVEVSAED LLTCCGSMCG DGCNGGYPAE AWNFWTRKGL VSGGLYESHV GCRPYSIPPC EHHVNGSRPP CTGEGDTPKC SKICEPGYSP TYKQDKHYGY NSYSVSNSEK DIMAEIYKNG PVEGAFSVYS DFLLYKSGVY QHVTGEMMGG HAIRILGWGV ENGTPYWLVA NSWNTDWGDN GFFKILRGQD HCGIESEVVA GIPRTDQYWE KI
Positive Samples: A375, HepG2, HT-1080, MCF7, A-549, Mouse liver, Rat kidney; Cellular Location: Lysosome, Melanosome, extracellular space
靶标信息
Cathepsin B is a lysosomal cysteine protease that has been implicated in the pathogenesis of rheumatoid arthritis, muscular dystrophy and tumor metastasis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: amyloid precursor protein secretase; APP secretase; APPS; Cathepsin B; Cathepsin B1; cysteine protease; RSG-2
基因别名: APPS; CB; CPSB; CTSB
UniProt ID: (Human) P07858, (Mouse) P10605
Entrez Gene ID: (Human) 1508, (Rat) 64529, (Mouse) 13030
cysteine-type endopeptidase activity
serine-type endopeptidase activity
protein binding
collagen binding
peptidase activity
cysteine-type peptidase activity
kininogen binding
peptide binding
proteoglycan binding
protein self-association
endopeptidase activity
protein complex binding
hydrolase activity
cysteine protease
toll-like receptor signaling pathway
proteolysis
autophagy
spermatogenesis
skeletal muscle tissue development
response to wounding
response to glucose
response to organic cyclic compound
response to amine
collagen catabolic process
epithelial cell differentiation
regulation of apoptotic process
response to peptide hormone
response to ethanol
decidualization
viral entry into host cell
regulation of catalytic activity
proteolysis involved in cellular protein catabolic process
negative regulation of cell death
response to interleukin-4
cellular response to mechanical stimulus
cellular response to thyroid hormone stimulus
response to mechanical stimulus
response to cytokine
