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Product Details
MA5-42576
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Zebrafish
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
J11-A11
Immunogen
Synthetic peptide within human cathepsin b aa 300-338
Conjugate
Form
Liquid
Concentration
2 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 40% glycerol, 0.2% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2911717
Product Specific Information
Positive Control: SW480, HepG2
Subcellular Location: Lysosome, secreted
Target Information
Cathepsin B is a lysosomal cysteine protease that has been implicated in the pathogenesis of rheumatoid arthritis, muscular dystrophy and tumor metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: amyloid precursor protein secretase; APP secretase; APPS; capthepsin B, b; Cathepsin B; cathepsin B, a; Cathepsin B1; cysteine protease
Gene Aliases: APPS; CPSB; CTSB; id:ibd1201; wu:fa13g05; wu:fb34e12; zgc:55862; zgc:65809; zgc:77181
UniProt ID: (Human) P07858
Entrez Gene ID: (Human) 1508, (Zebrafish) 406645, (Zebrafish) 569298
toll-like receptor signaling pathway
proteolysis
autophagy
spermatogenesis
skeletal muscle tissue development
response to wounding
response to glucose
response to organic cyclic compound
response to amine
collagen catabolic process
epithelial cell differentiation
regulation of apoptotic process
response to peptide hormone
response to ethanol
decidualization
viral entry into host cell
regulation of catalytic activity
proteolysis involved in cellular protein catabolic process
negative regulation of cell death
response to interleukin-4
cellular response to mechanical stimulus
cellular response to thyroid hormone stimulus
dorsal/ventral pattern formation
fin regeneration
convergent extension
epiboly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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