Invitrogen

Cathepsin H Polyclonal Antibody

Cathepsin H Antibody in Immunohistochemistry (Frozen) (IHC (F))

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Cathepsin H Antibody (PA5-47041) in IHC (F)

Immunohistochemical analysis of Cathepsin H in perfusion fixed frozen sections of mouse ovary. Samples were incubated in Cathepsin H polyclonal antibody (Product # PA5-47041) using a dilution of 1.7 µg/mL overnight at 4 °C. Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown) and counterstained with hematoxylin (blue).

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产品信息

PA5-47041

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.1 µg/mL

免疫组化（冰冻） (IHC (F))

5-15 µg/mL

免疫沉淀 (IP)

25 µg/mL

产品规格

种属反应

Mouse

宿主/亚型

Goat / IgG

分类

Polyclonal

类型

Antibody

抗原

Mouse myeloma cell line NS0-derived recombinant mouse Cathepsin H Glu22-Val333

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.2 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS with 5% trehalose

内含物

No Preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2608644

产品详细信息

In direct ELISAs and Western blots, approximately 25% cross-reactivity with recombinant human (rh) Cathepsin H is observed and less than 2% cross-reactivity with recombinant mouse (rm) Cathepsin B, rmCathepsin C, rmCathepsin Z, rmCathepsin L, and rhCathepsin O is observed.

Reconstitute at 0.2 mg/mL in sterile PBS.

靶标信息

The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in various cellular events such as peptide biosynthesis and protein degradation. The propeptide region of cathepsin H is highly homologous to other cathepsins. This region is thought to play a role in the processing of cysteine proteases. Cathepsin H is thought to be involved in several pathological conditions, including neuro degenerative disorders and cancer.

仅用于科研。不用于诊断过程。未经明确授权不得转售。