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Cathepsin H Antibody (MA5-55359) in WB
Western Blot analysis of various lysates using Cathepsin H Recombinant Monoclonal Antibody (Product # MA5-55359) at 1:1,000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1:10,000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
产品信息
MA5-55359
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
3C2F4
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 150-250 of human Cathepsin H.
偶联物
形式
Liquid
浓度
1.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
产品详细信息
Immunogen Sequence: LESAIAIATG KMLSLAEQQL VDCAQDFNNH GCQGGLPSQA FEYILYNKGI MGEDTYPYQG KDGYCKFQPG KAIGFVKDVA NITIYDEEAM VEAVALYNPV S
靶标信息
The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in various cellular events such as peptide biosynthesis and protein degradation. The propeptide region of cathepsin H is highly homologous to other cathepsins. This region is thought to play a role in the processing of cysteine proteases. Cathepsin H is thought to be involved in several pathological conditions, including neuro degenerative disorders and cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: aleurain; Cat H; CATH; Cathepsin B3; Cathepsin BA; N-benzoylarginine-beta-naphthylamide hydrolase; Pro-cathepsin H
基因别名: ACC-4; ACC-5; ACC4; ACC5; AL022844; CPSB; CTSH
UniProt ID: (Human) P09668, (Mouse) P49935
Entrez Gene ID: (Human) 1512, (Mouse) 13036
endopeptidase activity
aminopeptidase activity
cysteine-type endopeptidase activity
serine-type endopeptidase activity
protein binding
peptidase activity
cysteine-type peptidase activity
cysteine-type endopeptidase activator activity involved in apoptotic process
HLA-A specific activating MHC class I receptor activity
thyroid hormone binding
peptidase activator activity involved in apoptotic process
hydrolase activity
kininogen binding
protein complex binding
protein self-association
cysteine protease
metanephros development
T cell mediated cytotoxicity
adaptive immune response
immune response-regulating signaling pathway
proteolysis
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of cell proliferation
positive regulation of gene expression
positive regulation of epithelial cell migration
neuropeptide catabolic process
bradykinin catabolic process
positive regulation of peptidase activity
antigen processing and presentation
positive regulation of cell migration
zymogen activation
protein destabilization
response to retinoic acid
membrane protein proteolysis
negative regulation of apoptotic process
surfactant homeostasis
cellular protein metabolic process
positive regulation of angiogenesis
proteolysis involved in cellular protein catabolic process
dichotomous subdivision of terminal units involved in lung branching
ERK1 and ERK2 cascade
cellular response to thyroid hormone stimulus
positive regulation of apoptotic signaling pathway
