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Immunogen sequence: AVWEKNMKMI ELHNQEYREG KHSFTMAMNA FGDMTSEEFR QVMNGFQNRK PRKGKVFQEP LFYEAPRSVD WREKGYVTPV KNQGQCGSCW AFSATGALEG Q
The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: aleurain; Cat H; Cat K; Cat L; Cathepsin B3; Cathepsin BA; Cathepsin K; Cathepsin L1; Cathepsin L2; cathepsin L2, preproprotein; Cathepsin O; cathepsin O1; Cathepsin O2; Cathepsin U; Cathepsin V; Cathepsin X; CP-2; Cyclic protein 2; furless; Major excreted protein; MEP; minisatellite 10q detected by probe MMS10; N-benzoylarginine-beta-naphthylamide hydrolase; nackt; p39 cysteine proteinase; Pro-cathepsin H; Procathepsin L
基因别名: 1190035F06Rik; ACC-4; ACC-5; ACC4; ACC5; AI323530; AL022844; CATHL; catK; CATL; CATL2; CPSB; CTS02; CTSH; CTSK; CTSL; CTSL1; CTSL2; CTSO; CTSO1; CTSO2; CTSU; CTSV; fs; MEP; MMS10-Q; Ms10q; nkt; PKND; PYCD; UNQ268/PRO305
UniProt ID: (Human) P09668, (Human) P43235, (Human) P07711, (Human) O60911, (Rat) P00786, (Mouse) P49935, (Rat) O35186, (Mouse) P55097, (Mouse) P06797, (Rat) P07154
Entrez Gene ID: (Human) 1512, (Human) 1513, (Human) 1514, (Human) 1515, (Rat) 25425, (Mouse) 13036, (Rat) 29175, (Mouse) 13038, (Mouse) 13039, (Rat) 25697