Invitrogen

Cathepsin K Polyclonal Antibody

Cathepsin K Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 3

Cathepsin K Antibody (PA5-18950) in ICC/IF

Immunocytochemistry analysis of Cathepsin K using Cathepsin K Polyclonal Antibody (Product # PA5-18950) in paraformaldehyde fixed U2OS cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (2 µg/mL), showing vesicle staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 µg/mL) followed by Alexa Fluor 488 secon... View More

Cathepsin K Antibody in Western Blot (WB)

Product Image Gallery

产品信息

PA5-18950

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.1-1 µg/mL

免疫细胞化学 (ICC/IF)

10 µg/mL

产品规格

种属反应

Human, Rat

宿主/亚型

Goat / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide sequence (KTHRKQYNNKVDE) corresponding to the internal amino acids of CTSK (aa 31-44).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Ammonium sulfate precipitation

保存液

TBS, pH 7.3, with 0.5% BSA

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_10981412

产品详细信息

This antibody is predicted to react with bovine, canine, mouse, porcine and rat based on sequence homology.

This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

靶标信息

The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.

仅用于科研。不用于诊断过程。未经明确授权不得转售。