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Product Details
PA5-112393
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Cathepsin L2 protein (105-334AA)
Conjugate
Form
Liquid
Concentration
1.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Wet ice
RRID
AB_2867128
Target Information
Cathepsin V (CTSU, CTSV, CATL2, cathepsin U, cathepsin L2) is a lysosomal cysteine proteinase that influences corneal physiology, and mediates degradation of invariant chain in human thymus. Cathepsin V is present in corneal epithelium, activated macrophages, and colorectal and breast carcinomas. A 1.8-kb mRNA to Cathepsin V is present in normal human thymus and testis. Cathepsin V is a member of the peptidase C1 family. Cysteine proteinases are synthesized as preproenzymes, which are processed to the corresponding proenzymes. The proenzymes are either targeted to the lysosome or continue along the cellular secretory route.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cathepsin L2; cathepsin L2, preproprotein; Cathepsin U; Cathepsin V; PRO305; UNQ268
Gene Aliases: CATL2; CTSL2; CTSU; CTSV; UNQ268/PRO305
UniProt ID: (Human) O60911
Entrez Gene ID: (Human) 1515
spermatogenesis
cellular response to starvation
response to glucose
multicellular organism aging
negative regulation of keratinocyte proliferation
protein autoprocessing
antigen processing and presentation of exogenous peptide antigen via MHC class II
nerve development
extracellular matrix disassembly
hair follicle morphogenesis
response to gonadotropin
decidualization
autophagic cell death
response to glucocorticoid
proteolysis involved in cellular protein catabolic process
Sertoli cell differentiation
regulation of actin cytoskeleton reorganization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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