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Positive Samples: HeLa, A-549, Mouse liver, Rat liver
Immunogen sequence: VFREPLFLDL PKSVDWRKKG YVTPVKNQKQ CGSCWAFSAT GALEGQMFRK TGKLVSLSEQ NLVDCSRPQG NQGCNGGFMA RAFQYVKENG GLDSEESYPY VAVDEICKYR PENSVANDTG FTVVAPGKEK ALMKAVATVG PISVAMDAGH SSFQFYKSGI YFEPDCSSKN LDHGVLVVGY GFEGANSNNS KYWLVKNSWG PEWGSNGYVK IAKDKNNHCG IATAASYPNV
Cathepsin V (CTSU, CTSV, CATL2, cathepsin U, cathepsin L2) is a lysosomal cysteine proteinase that influences corneal physiology, and mediates degradation of invariant chain in human thymus. Cathepsin V is present in corneal epithelium, activated macrophages, and colorectal and breast carcinomas. A 1.8-kb mRNA to Cathepsin V is present in normal human thymus and testis. Cathepsin V is a member of the peptidase C1 family. Cysteine proteinases are synthesized as preproenzymes, which are processed to the corresponding proenzymes. The proenzymes are either targeted to the lysosome or continue along the cellular secretory route.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cathepsin L2; cathepsin L2, preproprotein; Cathepsin U; Cathepsin V; PRO305; UNQ268
基因别名: CATL2; CTSL2; CTSU; CTSV; UNQ268/PRO305
UniProt ID: (Human) O60911
Entrez Gene ID: (Human) 1515