NeoBiotechnologies

Cdc20 (Cell Division Cycle Protein 20) Monoclonal Antibody (AR12)

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抗体检测数据 (3)

Cdc20 (Cell Division Cycle Protein 20) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Cdc20 (Cell Division Cycle Protein 20) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Cdc20 (Cell Division Cycle Protein 20) Antibody (991-MSM1-P0) in IHC (P)

Formalin-fixed, paraffin-embedded human Gastric Carcinoma stained with CDC20 Mouse Monoclonal Antibody (AR12).

Cdc20 (Cell Division Cycle Protein 20) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Cdc20 (Cell Division Cycle Protein 20) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Cdc20 (Cell Division Cycle Protein 20) Antibody in SDS-PAGE (SDS-PAGE)

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Cdc20 (Cell Division Cycle Protein 20) Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Formalin-fixed, paraffin-embedded human Gastric Carcinoma stained with CDC20 Mouse Monoclonal Antibody (AR12).

Cdc20 (Cell Division Cycle Protein 20) Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Formalin-fixed, paraffin-embedded human Tonsil stained with CDC20 Mouse Monoclonal Antibody (AR12).

Cdc20 (Cell Division Cycle Protein 20) Antibody in SDS-PAGE (SDS-PAGE) — SDS-PAGE analysis Purified CDC20 Mouse Monoclonal Antibody (AR12). Confirmation of Purity and Integrity of Antibody.

产品信息

991-MSM1-P0

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

Assay-dependent

-

免疫组织化学（多聚甲醛固定） (IHC (PFA))

1-2 µg/mL

-

免疫细胞化学 (ICC/IF)

1-2 µg/mL

-

流式细胞分析 (Flow)

1-2 µg/10^6 cells

-

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

AR12

抗原

Urea-denatured His6 Cdc20 human recombinant protein

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

200 µg/mL

纯化类型

Protein A/G

保存液

PBS, pH 7.4, with 0.05% BSA

内含物

0.05% sodium azide

保存条件

4° C, do not freeze

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: CDC20 cell division cycle 20 homolog; cell division cycle 20 homolog; Cell division cycle protein 20 homolog; p55CDC

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基因别名: bA276H19.3; CDC20; CDC20A; p55CDC

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UniProt ID: (Human) Q12834

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Entrez Gene ID: (Human) 991

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protein binding protein C-terminus binding anaphase-promoting complex binding enzyme binding histone deacetylase binding ubiquitin-protein transferase activator activity ubiquitin-protein ligase

cell cycle sister chromatid cohesion mitotic nuclear division positive regulation of cell proliferation anaphase-promoting complex-dependent catabolic process positive regulation of synaptic plasticity regulation of meiotic nuclear division protein ubiquitination involved in ubiquitin-dependent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process regulation of dendrite development cell division negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle positive regulation of synapse maturation positive regulation of ubiquitin protein ligase activity