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Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji, mouse liver.
Predicted reactivity: Mouse (87%), Rat (86%), Pig (90%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. COASY is a bifunctional enzyme that catalyzes the 2 last steps in CoA synthesis. These activities are performed by 2 separate enzymes, phosphopantetheine adenylyltransferase and dephospho-CoA kinase, in prokaryotes.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Bifunctional coenzyme A synthase; bifunctional phosphopantetheine adenylyl transferase/dephospho CoA kinase; CoA synthase; NBP; nucleotide binding protein; phosphopantetheine adenylyltransferase / dephosphocoenzyme A kinase; POV-2
Gene Aliases: 1300003G02Rik; COASY; DPCK; NBIA6; NBP; pOV-2; PPAT; PSEC0106; UKR1
UniProt ID: (Human) Q13057, (Mouse) Q9DBL7
Entrez Gene ID: (Human) 80347, (Mouse) 71743
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