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产品信息
720-MSM1-P1ABX
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
C4D204
抗原
Recombinant full-length human Complement 4d protein
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Antibody is tested in direct ELISA (For coating use Ab at 1-2 µg/mL.
Immunohistochemistry (PFA fixed): incubate antibody for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 1mM EDTA, pH 7.5-8.5, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.
靶标信息
C4 is a component of the classical complement pathway and is split by activated C1s to C4a and C4b. Together C2a and C4b forms the classical C3 convertase. The molecular mass of C4 is 204 kDa and it consists of 3 subunits: a (97 kDa), b (75 kDa) and g (33 kDa).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: acidic C4; Acidic complement C4; Basic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3; c4 complement; C4A anaphylatoxin; C4D; Chido form of C4; Complement C4-A; Complement C4-B; complement C4B1a; DADB-112B14.11; FLJ60561; MGC164979; MHC class III region complement; Rodgers form of C4
基因别名: C4; C4A; C4A2; C4A3; C4A4; C4A6; C4AD; C4B; C4B1; C4B12; C4B2; C4B3; C4B5; C4B_2; C4BD; C4F; C4S; CH; CO4; CPAMD2; CPAMD3; RG
UniProt ID: (Human) P0C0L4, (Human) Q4LE82, (Human) P0C0L5
Entrez Gene ID: (Human) 720, (Human) 721, (Human) 100293534
proteolysis
inflammatory response
complement activation
complement activation, classical pathway
negative regulation of endopeptidase activity
regulation of complement activation
innate immune response
positive regulation of apoptotic cell clearance
opsonization
detection of molecule of bacterial origin
