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产品信息
MA1-83965
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Baboon
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
053A-1149.3.1.4 (1003)
抗原
Purified C3d from human plasma.
偶联物
形式
Liquid
浓度
1.13 mg/mL
纯化类型
Protein A
保存液
BBS, pH 8.4
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_930156
产品详细信息
Mouse anti Human C3d antibody, clone 053A-1149.3.1.4 recognizes human complement component 3d (C3d), a approximately 33 kDa polypeptide fragment generated over the course of complement activation where complement 3 (C3) convertases cleave C3 to C3b, which is further degraded into iC3b and C3dg/C3d.
靶标信息
C3 is a key component of the complement system since classical and alternative activation pathways merge at the C3 activation step when C3 is split into C3a and C3b. The molecular mass of C3 is 185 kDa and it consists of two chains (110 kDa and 75 kDa) held together by disulfide bonds.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Acylation stimulating protein cleavage product; acylation-stimulating protein cleavage product; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a anaphylatoxin; Cd3; chain fragment 2; Complement C3; Complement C3c alpha' complement component C3a; complement component C3b; epididymis secretory sperm binding protein Li 62p; prepro-C3
基因别名: AHUS5; ARMD9; ASP; C3; C3a; C3b; CPAMD1; HEL-S-62p
UniProt ID: (Human) P01024
Entrez Gene ID: (Human) 718
positive regulation of type IIa hypersensitivity
positive regulation of protein phosphorylation
positive regulation of activation of membrane attack complex
tolerance induction
proteolysis
fatty acid metabolic process
inflammatory response
immune response
complement activation
complement activation, alternative pathway
complement activation, classical pathway
signal transduction
G-protein coupled receptor signaling pathway
blood coagulation
positive regulation of vascular endothelial growth factor production
positive regulation of glucose transport
regulation of triglyceride biosynthetic process
positive regulation of lipid storage
negative regulation of endopeptidase activity
regulation of complement activation
response to magnesium ion
response to estradiol
response to progesterone
response to estrogen
positive regulation of G-protein coupled receptor protein signaling pathway
positive regulation of angiogenesis
positive regulation of developmental growth
regulation of immune response
response to glucocorticoid
positive regulation of ERK1 and ERK2 cascade
positive regulation of apoptotic cell clearance
