Invitrogen

Connexin 31 Polyclonal Antibody

Connexin 31 Antibody in Western Blot (WB)

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Connexin 31 Antibody (PA5-113757) in WB

Western Blot of Mouse SP2/0 using a Connexin 31 Polyclonal Antibody (Product # PA5-113757).

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产品信息

PA5-113757

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.125 µg/mL

产品规格

种属反应

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide directed towards the N-terminal region of Mouse Gjb3 (aa 1-50).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Affinity chromatography

保存液

PBS with 2% sucrose

内含物

0.09% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_2884272

产品详细信息

Immunogen sequence: MDWKKLQDLL SGVNQYSTAF GRIWLSVVFV FRVLVYVVAA ERVWGDEQKD

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Predicted homology: Cow: 79%; Dog: 83%; Horse: 83%; Human: 83%; Mouse: 100%; Pig: 83%; Rabbit: 79%; Rat: 100%; Zebrafish: 92%

靶标信息

Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. Defects in GJB3 have been linked to erythrokeratodermia variabilis (EKV) is an autosomal dominant genodermatosis characterized by transient figurate red patches or hyperkeratosis. Mutations in GJB2 have also been associated with genetically derived hearing impairments, including autosomal recessive nonsyndromic deafness.

仅用于科研。不用于诊断过程。未经明确授权不得转售。