Product References
Electrical synapse structure requires distinct isoforms of a postsynaptic scaffold.
PLoS genetics
Michel JC,Grivette MMB,Harshfield AT,Huynh L,Komons AP,Loomis B,McKinnis K,Miller BT,Nguyen EQ,Huang TW,Lauf S,Michel ES,Michel ME,Kissinger JS,Marsh AJ,Crow WE,Kaye LE,Lasseigne AM,Lukowicz-Bedford RM,Farnsworth DR,Martin EA,Miller AC
36-4600 was used in Immunohistochemistry to propose that ESD molecular complexity arises both from the diversity of unique genes and from distinct isoforms encoded by single genes.
Wed Nov 01 00:00:00 UTC 2023
The disconnect2 mutation disrupts the tjp1b gene that is required for electrical synapse formation.
microPublication biology
Michel JC,Lasseigne AM,Marsh AJ,Miller AC
36-4600 was used in Immunohistochemistry to investigate electrical synapse formation in vivo we used forward genetics to disrupt genes affecting Mauthner cell electrical synapses in larval zebrafish.
Tue Sep 12 00:00:00 UTC 2023
Functional connexin35 increased in the myopic chicken retina.
Visual neuroscience
Banerjee S,Wang Q,Tang G,So C,Shan SW,Li KK,Do CW,Pan F
36-4600 was used in Western Blot to determine whether phosphorylation at serine 276 of Cx35-containing gap junctions increased in the myopic chicken, whose retina is cone-dominant. Refractive errors and ocular biometric dimensions of 7-days-old chickens were determined following 12 h and 7 days induction of myo.
Fri May 14 00:00:00 UTC 2021
Reduced synchroneity of intra-islet Ca2+ oscillations in vivo in Robo-deficient β cells.
eLife
Adams MT,Dwulet JM,Briggs JK,Reissaus CA,Jin E,Szulczewski JM,Lyman MR,Sdao SM,Kravets V,Nimkulrat SD,Ponik SM,Merrins MJ,Mirmira RG,Linnemann AK,Benninger RK,Blum B
36-4600 was used in ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to provide evidence that this loss is not due to a β cell-intrinsic function of Robo, mis-expression or mis-localization of Cx36 gap junctions, or changes in islet vascularization or innervation, suggesting that the islet architecture itself is required for synchronized Ca2+ oscillations.
Wed Jul 07 00:00:00 UTC 2021
Neuronal Glutamatergic Network Electrically Wired with Silent But Activatable Gap Junctions.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Ixmatlahua DJ,Vizcarra B,Gómez-Lira G,Romero-Maldonado I,Ortiz F,Rojas-Piloni G,Gutiérrez R
36-4600 was used in Immunocytochemistry to reveal that electrical synapses are pH sensitive, actuate in vitro and in vivo, and that the electrical signaling is bidirectional.
Wed Jun 10 00:00:00 UTC 2020
Rod Photoreceptors Signal Fast Changes in Daylight Levels Using a Cx36-Independent Retinal Pathway in Mouse.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Pasquale R,Umino Y,Solessio E
36-4600 was used in Immunohistochemistry-immunofluorescence to investigate rod-driven, temporal contrast sensitivity (TCS) in mice of either sex.
Wed Jan 22 00:00:00 UTC 2020
Effects of Constitutive and Acute Connexin 36 Deficiency on Brain-Wide Susceptibility to PTZ-Induced Neuronal Hyperactivity.
Frontiers in molecular neuroscience
Brunal AA,Clark KC,Ma M,Woods IG,Pan YA
36-4600 was used in Immunohistochemistry (PFA fixed) to demonstrate a reciprocal relationship between Cx36 and seizure-associated neuronal hyperactivity: Cx36 deficiency contributes region-specific susceptibility to neuronal hyperactivity, while neuronal hyperactivity-induced downregulation of Cx36 may increase the risk of future epileptic events.
Sat Jan 30 00:00:00 UTC 2021
Increased Connexin36 Phosphorylation in AII Amacrine Cell Coupling of the Mouse Myopic Retina.
Frontiers in cellular neuroscience
Banerjee S,Wang Q,Zhao F,Tang G,So C,Tse D,To CH,Feng Y,Zhou X,Pan F
36-4600 was used in Immunocytochemistry to evaluate the expression patterns of connexin36-positive plaques (structural assay) and the state of connexin36 phosphorylation (functional assay) in AII ACs, which was green fluorescent protein-expressing in the Fam81a mouse line.
Mon Sep 28 00:00:00 UTC 2020
Phosphorylation of Connexin36 near the C-terminus switches binding affinities for PDZ-domain and 14-3-3 proteins in vitro.
Scientific reports
Tetenborg S,Wang HY,Nemitz L,Depping A,Espejo AB,Aseervatham J,Bedford MT,Janssen-Bienhold U,O'Brien J,Dedek K
36-4600 was used in Immunocytochemistry-immunoflourescence to reveal that phosphorylation sites may serve as a molecular switch and influence the affinity of the PDZ binding domain for its binding partners.
Tue Oct 27 00:00:00 UTC 2020
Gap Junctions in A8 Amacrine Cells Are Made of Connexin36 but Are Differently Regulated Than Gap Junctions in AII Amacrine Cells.
Frontiers in molecular neuroscience
Yadav SC,Tetenborg S,Dedek K
36-4600 was used in Immunohistochemistry-immunofluorescence to study the electrical synapses of A8 amacrine cells.
Wed Sep 30 00:00:00 UTC 2020
Downregulation of Neuronal and Dendritic Connexin36-Made Electrical Synapses Without Glutamatergic Axon Terminals in Spinal Anterior Horn Cells From the Early Stage of Amyotrophic Lateral Sclerosis.
Frontiers in neuroscience
Kobayakawa Y,Masaki K,Yamasaki R,Shiraishi W,Hayashida S,Hayashi S,Okamoto K,Matsushita T,Kira JI
36-4600 was used in Immunohistochemistry to study whether electrical synapses are involved in the pathogenesis of amyotrophic lateral sclerosis.
Tue Sep 29 00:00:00 UTC 2020
Asymmetry of an Intracellular Scaffold at Vertebrate Electrical Synapses.
Current biology : CB
Marsh AJ,Michel JC,Adke AP,Heckman EL,Miller AC
36-4600 was used in Immunohistochemistry-immunofluorescence to study the requirement of tight junction protein 1b in the formation of electrical synapses in vivo.
Mon Nov 20 00:00:00 UTC 2017
Differential Distribution of Retinal Ca2+/Calmodulin-Dependent Kinase II (CaMKII) Isoforms Indicates CaMKII-β and -δ as Specific Elements of Electrical Synapses Made of Connexin36 (Cx36).
Frontiers in molecular neuroscience
Tetenborg S,Yadav SC,Hormuzdi SG,Monyer H,Janssen-Bienhold U,Dedek K
36-4600 was used in Immunohistochemistry to identify Ca2+/calmodulin-dependent protein kinase II (CaMKII)-Β and -δ as connexin36-specific regulators in the mouse retina with CaMKII-δ regulating the primary rod pathway.
Wed Sep 30 00:00:00 UTC 2020
Structural organization of the dendritic reticulum linked by gap junctions in layer 4 of the visual cortex.
Neuroscience
Fukuda T
364600 was used in immunohistochemistry to find net-like dense linkages of dendrites among 96.6% of parvalbumin neurons in layer 4 of the feline visual cortex
Fri Jan 06 00:00:00 UTC 2017
A genetic basis for molecular asymmetry at vertebrate electrical synapses.
eLife
Miller AC,Whitebirch AC,Shah AN,Marsden KC,Granato M,O'Brien J,Moens CB
36-4600 was used in Immunohistochemistry to identify two connexins used asymmetrically for the formation and function of electrical synapses in zebrafish.
Mon May 22 00:00:00 UTC 2017
Gap Junctions Contribute to the Regulation of Walking-Like Activity in the Adult Mudpuppy (Necturus Maculatus).
PloS one
Lavrov I,Fox L,Shen J,Han Y,Cheng J
36-4600 was used in immunohistochemistry to analyze the Necturus Maculatus (adult mudpuppy) and how gap junctions contribute to the regulation of walking-like activity
Fri Aug 05 00:00:00 UTC 2016
Low Level Pro-inflammatory Cytokines Decrease Connexin36 Gap Junction Coupling in Mouse and Human Islets through Nitric Oxide-mediated Protein Kinase Cδ.
The Journal of biological chemistry
Farnsworth NL,Walter RL,Hemmati A,Westacott MJ,Benninger RK
36-4600 was used in immunohistochemistry to assess how nitric oxide-mediated protein kinase Cdelta decreases connexin36 gap junction coupling in human and mouse islets due to cytokines
Fri Feb 12 00:00:00 UTC 2016
Gain-of-function nature of Cav1.4 L-type calcium channels alters firing properties of mouse retinal ganglion cells.
Channels (Austin, Tex.)
Knoflach D,Schicker K,Glösmann M,Koschak A
36-4600 was used in immunohistochemistry to study alteration of firing properties of mouse retinal ganglion cells due to the gain-of-function nature of Cav1.4 L-type calcium channels
Fri Aug 19 00:00:00 UTC 2016
Functional alterations in gut contractility after connexin36 ablation and evidence for gap junctions forming electrical synapses between nitrergic enteric neurons.
FEBS letters
Nagy JI,Urena-Ramirez V,Ghia JE
36-4600 was used in immunohistochemistry to investigate gap junction-mediated communcation between nitrergic enteric neurons
Thu Apr 17 00:00:00 UTC 2014
Connexin36 in gap junctions forming electrical synapses between motoneurons in sexually dimorphic motor nuclei in spinal cord of rat and mouse.
The European journal of neuroscience
Bautista W,Nagy JI
36-4600 was used in immunocytochemistry to identify gap junction-mediated communcation between motoneurons in sexually dimorphic motor nuclei in spinal cord of rat and mouse
Sat Mar 01 00:00:00 UTC 2014
Reciprocal regulation of epileptiform neuronal oscillations and electrical synapses in the rat hippocampus.
PloS one
Kinjo ER,Higa GS,Morya E,Valle AC,Kihara AH,Britto LR
36-4600 was used in immunohistochemistry and western blot to investigate the interrelationship between epileptiform neuronal oscillations and electrical synapses in the rat hippocampus
Tue Jun 16 00:00:00 UTC 2015
Abundance of gap junctions at glutamatergic mixed synapses in adult Mosquitofish spinal cord neurons.
Frontiers in neural circuits
Serrano-Velez JL,Rodriguez-Alvarado M,Torres-Vazquez II,Fraser SE,Yasumura T,Vanderpool KG,Rash JE,Rosa-Molinar E
36-4600 was used in immunohistochemistry to investigate the role of gap junctions in fast motor behavior
Wed Sep 24 00:00:00 UTC 2014
Molecular and functional asymmetry at a vertebrate electrical synapse.
Neuron
Rash JE,Curti S,Vanderpool KG,Kamasawa N,Nannapaneni S,Palacios-Prado N,Flores CE,Yasumura T,O'Brien J,Lynn BD,Bukauskas FF,Nagy JI,Pereda AE
36-4600 was used in immunocytochemistry to investigate the functional and molecular complexities of electrical synapses in fish.
Wed Sep 04 00:00:00 UTC 2013
The rod pathway of the microbat retina has bistratified rod bipolar cells and tristratified AII amacrine cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Müller B,Butz E,Peichl L,Haverkamp S
36-4600 was used in immunohistochemistry - frozen section to investigate the retinal rod pathway of Carollia perspicillata and Glossophaga soricina.
Wed Jan 16 00:00:00 UTC 2013
Morphologically mixed chemical-electrical synapses formed by primary afferents in rodent vestibular nuclei as revealed by immunofluorescence detection of connexin36 and vesicular glutamate transporter-1.
Neuroscience
Nagy JI,Bautista W,Blakley B,Rash JE
36-4600 was used in Immunohistochemistry-immunofluorescence to investigate the distribution and cellular localisation of electrical synapses in the adult and developing rodent vestibular nuclear complex.
Tue Nov 12 00:00:00 UTC 2013
Morphologically mixed chemical-electrical synapses formed by primary afferents in rodent vestibular nuclei as revealed by immunofluorescence detection of connexin36 and vesicular glutamate transporter-1.
Neuroscience
Nagy JI,Bautista W,Blakley B,Rash JE
36-4600 was used in Immunohistochemistry-immunofluorescence to investigate the distribution and cellular localisation of electrical synapses in the adult and developing rodent vestibular nuclear complex.
Tue Nov 12 00:00:00 UTC 2013
Trafficking of gap junction channels at a vertebrate electrical synapse in vivo.
Proceedings of the National Academy of Sciences of the United States of America
Flores CE,Nannapaneni S,Davidson KG,Yasumura T,Bennett MV,Rash JE,Pereda AE
36-4600 was used in immunohistochemistry - frozen section to elucidate the trafficking of gap junction components at electrical synapses.
Tue Feb 28 00:00:00 UTC 2012
Synergy between electrical coupling and membrane properties promotes strong synchronization of neurons of the mesencephalic trigeminal nucleus.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Curti S,Hoge G,Nagy JI,Pereda AE
36-4600 was used in immunohistochemistry to study the properties, functional organization, and developmental emergence of electrical coupling in the mesencephalic trigeminal nucleus.
Wed Mar 28 00:00:00 UTC 2012
Pituitary adenylate cyclase-activating peptide enhances electrical coupling in the mouse adrenal medulla.
American journal of physiology. Cell physiology
Hill J,Lee SK,Samasilp P,Smith C
36-4600 was used in western blot to investigate if PACAP-mediated excitation upregulates cell-cell electrical coupling to enhance chromaffin cell excitability.
Wed Aug 01 00:00:00 UTC 2012
Behavioral alterations and changes in Ca/calmodulin kinase II levels in the striatum of connexin36 deficient mice.
Behavioural brain research
Zlomuzica A,Viggiano D,Degen J,Binder S,Ruocco LA,Sadile AG,Willecke K,Huston JP,Dere E
36-4600 was used in immunohistochemistry - free floating to report that Cx36 deficiency results in behavioral changes.
Sun Jan 01 00:00:00 UTC 2012
Cx36 is a target of Beta2/NeuroD1, which associates with prenatal differentiation of insulin-producing β cells.
The Journal of membrane biology
Nlend RN,Aït-Lounis A,Allagnat F,Cigliola V,Charollais A,Reith W,Haefliger JA,Meda P
36-4600 was used in immunohistochemistry - frozen section to investigate mechanisms that regulate connexin 36 expression.
Fri Jun 01 00:00:00 UTC 2012
Blocking of connexin-mediated communication promotes neuroprotection during acute degeneration induced by mechanical trauma.
PloS one
Paschon V,Higa GS,Resende RR,Britto LR,Kihara AH
36-4600 was used in immunohistochemistry - free floating to examine the role of connexin-mediated communication in a focal lesion induced by mechanical trauma of the retina.
Mon Feb 25 00:00:00 UTC 2013
Mixed Electrical-Chemical Synapses in Adult Rat Hippocampus are Primarily Glutamatergic and Coupled by Connexin-36.
Frontiers in neuroanatomy
Hamzei-Sichani F,Davidson KG,Yasumura T,Janssen WG,Wearne SL,Hof PR,Traub RD,Gutiérrez R,Ottersen OP,Rash JE
36-4600 was used in immunohistochemistry to report "mixed" (electrical/chemical) synapses on both principal cells and interneurons in adult rat hippocampus
Tue Oct 02 00:00:00 UTC 2012
Reorganization of gap junctions after focused ultrasound blood-brain barrier opening in the rat brain.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Alonso A,Reinz E,Jenne JW,Fatar M,Schmidt-Glenewinkel H,Hennerici MG,Meairs S
36-4600 was used in immunohistochemistry and western blot to report that ultrasound-induced opening of the blood brain barrier results in a reorganization of gap-junctional plaques in neurons and astrocytes
Thu Jul 01 00:00:00 UTC 2010
Distribution of the neuronal gap junction protein Connexin36 in the spinal cord enlargements of developing and adult opossums, Monodelphis domestica.
Brain, behavior and evolution
Lemieux M,Cabana T,Pflieger JF
36-4600 was used in immunohistochemistry and western blot to use opossums to study the development of mammalian motor systems
Tue Jun 15 00:00:00 UTC 2010
Network architecture of gap junction-coupled neuronal linkage in the striatum.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Fukuda T
36-4600 was used in immunohistochemistry to report a method to detect neuronal gap junctions and explore the network architecture of the gap junctional linkage
Wed Jan 28 00:00:00 UTC 2009
Connexin36, an essential element in the rod pathway, is highly expressed in the essentially rodless retina of Gallus gallus.
The Journal of comparative neurology
Kihara AH,Paschon V,Cardoso CM,Higa GS,Castro LM,Hamassaki DE,Britto LR
36-4600 was used in immunohistochemistry to study the express of connexin36 in Gallus gallus rod photoreceptors
Tue Feb 10 00:00:00 UTC 2009
Connexin45-containing neuronal gap junctions in rodent retina also contain connexin36 in both apposing hemiplaques, forming bihomotypic gap junctions, with scaffolding contributed by zonula occludens-1.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Li X,Kamasawa N,Ciolofan C,Olson CO,Lu S,Davidson KG,Yasumura T,Shigemoto R,Rash JE,Nagy JI
Wed Sep 24 00:00:00 UTC 2008
Connexin45-containing neuronal gap junctions in rodent retina also contain connexin36 in both apposing hemiplaques, forming bihomotypic gap junctions, with scaffolding contributed by zonula occludens-1.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Li X,Kamasawa N,Ciolofan C,Olson CO,Lu S,Davidson KG,Yasumura T,Shigemoto R,Rash JE,Nagy JI
Wed Sep 24 00:00:00 UTC 2008
A new conditional mouse mutant reveals specific expression and functions of connexin36 in neurons and pancreatic beta-cells.
Experimental cell research
Wellershaus K,Degen J,Deuchars J,Theis M,Charollais A,Caille D,Gauthier B,Janssen-Bienhold U,Sonntag S,Herrera P,Meda P,Willecke K
36-4600 was used in immunohistochemistry - frozen section to generate and characterize a conditional connexin36 deficient mouse mutant
Mon Mar 10 00:00:00 UTC 2008
Identification of connexin36 in gap junctions between neurons in rodent locus coeruleus.
Neuroscience
Rash JE,Olson CO,Davidson KG,Yasumura T,Kamasawa N,Nagy JI
36-4600 was used in immunohistochemistry to determine the abundance and connexin composition of neuronal and glial gap junctions in developing and adult rat and mouse locus coeruleus
Sun Jul 29 00:00:00 UTC 2007
Spatial relationships of connexin36, connexin57 and zonula occludens-1 in the outer plexiform layer of mouse retina.
Neuroscience
Ciolofan C,Lynn BD,Wellershaus K,Willecke K,Nagy JI
36-4600 was used in immunohistochemistry to investigate connexin57 expression in the mouse retina
Fri Aug 24 00:00:00 UTC 2007
Gap junctions among dendrites of cortical GABAergic neurons establish a dense and widespread intercolumnar network.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Fukuda T,Kosaka T,Singer W,Galuske RA
36-4600 was used in immunohistochemistry to study the gap junction-coupled networks of parvalbumin neurons
Wed Mar 29 00:00:00 UTC 2006
Novel interneuronal network in the mouse posterior piriform cortex.
The Journal of comparative neurology
Zhang C,Szabó G,Erdélyi F,Rose JD,Sun QQ
Wed Dec 20 00:00:00 UTC 2006
Expression of connexins 36, 43, and 45 during postnatal development of the mouse retina.
Journal of neurobiology
Kihara AH,Mantovani de Castro L,Belmonte MA,Yan CY,Moriscot AS,Hamassaki DE
36-4600 was used in immunohistochemistry to measure connexin expression during the postnatal development of the mouse retina
Wed Nov 01 00:00:00 UTC 2006
Different functional types of bipolar cells use different gap-junctional proteins.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Lin B,Jakobs TC,Masland RH
Wed Jul 13 00:00:00 UTC 2005
In vivo and in vitro expression of connexins in the human corneal epithelium.
Investigative ophthalmology & visual science
Shurman DL,Glazewski L,Gumpert A,Zieske JD,Richard G
Wed Jun 01 00:00:00 UTC 2005
Dye coupling in Purkinje cells of organotypic slice cultures.
Brain research. Developmental brain research
Meller K,Krah K,Theiss C
36-4600 was used in immunohistochemistry to correlate gap junctional intercellular communication and the development of Purkinje cells
Mon Nov 07 00:00:00 UTC 2005
Ultrastructural localization of connexins (Cx36, Cx43, Cx45), glutamate receptors and aquaporin-4 in rodent olfactory mucosa, olfactory nerve and olfactory bulb.
Journal of neurocytology
Rash JE,Davidson KG,Kamasawa N,Yasumura T,Kamasawa M,Zhang C,Michaels R,Restrepo D,Ottersen OP,Olson CO,Nagy JI
Thu Sep 01 00:00:00 UTC 2005
Neuronal connexin36 association with zonula occludens-1 protein (ZO-1) in mouse brain and interaction with the first PDZ domain of ZO-1.
The European journal of neuroscience
Li X,Olson C,Lu S,Kamasawa N,Yasumura T,Rash JE,Nagy JI
Thu Apr 01 00:00:00 UTC 2004
Neuronal connexin36 association with zonula occludens-1 protein (ZO-1) in mouse brain and interaction with the first PDZ domain of ZO-1.
The European journal of neuroscience
Li X,Olson C,Lu S,Kamasawa N,Yasumura T,Rash JE,Nagy JI
Thu Apr 01 00:00:00 UTC 2004
Neuronal connexin36 association with zonula occludens-1 protein (ZO-1) in mouse brain and interaction with the first PDZ domain of ZO-1.
The European journal of neuroscience
Li X,Olson C,Lu S,Kamasawa N,Yasumura T,Rash JE,Nagy JI
Thu Apr 01 00:00:00 UTC 2004
Association of connexin36 with zonula occludens-1 in HeLa cells, betaTC-3 cells, pancreas, and adrenal gland.
Histochemistry and cell biology
Li X,Olson C,Lu S,Nagy JI
36-4600 was used in immunohistochemistry, immunoprecipitation, and western blot to assess the association of connexin36 with ZO-1 in various cultured cells and tissues
Mon Nov 01 00:00:00 UTC 2004
High-resolution proteomic mapping in the vertebrate central nervous system: close proximity of connexin35 to NMDA glutamate receptor clusters and co-localization of connexin36 with immunoreactivity for zonula occludens protein-1 (ZO-1).
Journal of neurocytology
Rash JE,Pereda A,Kamasawa N,Furman CS,Yasumura T,Davidson KG,Dudek FE,Olson C,Li X,Nagy JI
Thu Jan 01 00:00:00 UTC 2004
