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Coronin 1A Antibody (PA5-28450) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of Coronin 1A was performed in DIV9 rat E18 primary cortical neuron cells fixed in 4% paraformaldehyde at RT for 15 min. Green: Coronin 1A Polyclonal Antibody (Product # PA5 28450) diluted at 1:500. Red: beta Tubulin 3/ Tuj1, stained by beta Tubulin 3/ Tuj1 antibody. Blue: Fluoroshield with DAPI.
Product Details
PA5-28450
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to a region within amino acids 399 and 461 of Human Coronin 1A
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2545926
Product Specific Information
Recommended positive controls: U87-MG, SK-N-SH, IMR32, SK-N-AS.
Predicted reactivity: Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Alternative splicing results in multiple transcript variants. A related pseudogene has been defined on chromosome 16.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: actin-binding; Clabp coronin; Clipin-A; coronin 1; coronin, actin binding protein, 1A; coronin-1; Coronin-1A; coronin-like actin binding protein; Coronin-like protein A; Coronin-like protein p57; FLJ41407; MGC117380; TACO; Tryptophan aspartate-containing coat protein
Gene Aliases: CLABP; CLIPINA; CORO1; CORO1A; HCORO1; IMD8; Lmb3; p57; TACO
UniProt ID: (Human) P31146, (Mouse) O89053, (Rat) Q91ZN1
Entrez Gene ID: (Human) 11151, (Mouse) 12721, (Rat) 155151
actin binding
actin monomer binding
protein binding
protein C-terminus binding
cytoskeletal protein binding
myosin heavy chain binding
protein homodimerization activity
phosphatidylinositol 3-kinase binding
poly(A) RNA binding
actin filament binding
identical protein binding
molecular_function
non-motor actin binding protein
immunological synapse formation
phagolysosome assembly
calcium ion transport
phagocytosis
movement of cell or subcellular component
actin filament organization
regulation of cell shape
actin cytoskeleton organization
positive regulation of cell migration
leukocyte chemotaxis
negative regulation of vesicle fusion
cell-substrate adhesion
uropod organization
regulation of actin cytoskeleton organization
nerve growth factor signaling pathway
positive regulation of T cell proliferation
T cell homeostasis
natural killer cell degranulation
negative regulation of neuron apoptotic process
innate immune response
homeostasis of number of cells within a tissue
positive chemotaxis
negative regulation of actin nucleation
regulation of release of sequestered calcium ion into cytosol
early endosome to recycling endosome transport
cellular response to interleukin-4
regulation of actin polymerization or depolymerization
cell migration
regulation of actin filament polymerization
response to cytokine
positive regulation of T cell activation
biological_process
T cell differentiation
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