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Invitrogen
Cyclin A2 Recombinant Rabbit Monoclonal Antibody (SD2052)
FIGURE: 1 / 8
Cyclin A2 Antibody (MA5-32353) in ICC/IF
Immunocytochemical analysis of Cyclin A2 in RH-35 cells using a Cyclin A2 Monoclonal antibody (Product # MA5-32353) as seen in green. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Product Details
MA5-32353
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
SD2052
Immunogen
Recombinant protein within mouse Cyclin A2 aa 1-240
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2809634
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
Cyclins are regulatory subunits of the cyclin-dependent kinases (cdks) and they control transition at different specific phases of the cell cycle. The temporal expression of cyclins is tightly regulated and subsequently plays a critical role in controlling the enzymatic activity of cdks. These cyclin / cdk complexes are essential for passage through specific stages in the cell cycle. In mammalian somatic cells, cyclin A is required for S phase and passage through G2-phase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cyclin A; Cyclin A2 (Cyclin A); Cyclin-A; Cyclin-A2
Gene Aliases: AA408589; Ccn-1; CCN1; CCNA; CCNA2; Cyca; CycA2
UniProt ID: (Human) P20248, (Mouse) P51943
Entrez Gene ID: (Human) 890, (Rat) 114494, (Mouse) 12428
regulation of cyclin-dependent protein serine/threonine kinase activity
mitotic nuclear division
mitotic G2 DNA damage checkpoint
Ras protein signal transduction
viral process
organ regeneration
response to glucagon
cellular response to platelet-derived growth factor stimulus
cellular response to leptin stimulus
positive regulation of transcription, DNA-templated
positive regulation of fibroblast proliferation
cell division
cellular response to cocaine
cellular response to luteinizing hormone stimulus
cellular response to estradiol stimulus
cellular response to hypoxia
cellular response to nitric oxide
cochlea development
cellular response to insulin-like growth factor stimulus
regulation of G2/M transition of mitotic cell cycle
response to estradiol
cell cycle
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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