Bethyl Laboratories

Cyclin C Polyclonal Antibody

Cyclin C Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Cyclin C Antibody (A301-989A) in IHC (P)

Detection of human Cyclin C by immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-Cyclin C (Product # A301-989A) (Lot 3) used at a dilution of 1:1,000 (1 µg/mL). Detection: DAB.

Cyclin C Antibody in Immunoprecipitation (IP)

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产品信息

A301-989A

应用

建议稀释比

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免疫印迹 (WB)

1:2,000-1:10,000

免疫组化 (IHC)

1:1,000-1:5,000

免疫组化（石蜡） (IHC (P))

1:1,000-1:5,000

免疫沉淀 (IP)

2-10 µg/mg lysate

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Region between residue 233 and 283 of human cyclin C.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

tris citrate/phosphate, pH 7-8

内含物

0.09% sodium azide

保存条件

4° C

运输条件

Wet ice

产品详细信息

The recommended shelf life for this product is 1 year from date of receipt.

Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 or Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Chicken and Bovine

靶标信息

Cyclin C was originally identified by a genetic screen for human and Drosophila cDNAs that complement a triple knock out of the CLN genes in Saccharomyces cerevisiae. Cyclin C is a nuclear protein present in a multiprotein complex. It interacts both in vitro and in vivo with cdk 8, a novel protein kinase of the cdk family. It is suggested that cyclin C and cdk 8 control RNA polymerase II function. Human cdk 8 cyclin C might be functionally associated with the mammalian transcription apparatus, perhaps involved in relaying growth regulatory signals.

仅用于科研。不用于诊断过程。未经明确授权不得转售。