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产品信息
PA1-31545
产品规格
种属反应
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide with sequence GTHSLTKFSCKNA, from C Terminus of the protein sequence according to NP_034106
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2088178
产品详细信息
Positive control of mouse kidney lysate suggested.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Cystatin C, a member of the type 2 cystatin superfamily, is a potent inhibitor of cysteine proteinases, both endogenous (lysosomal cathepsins), and pathogenic. Cystatin C is a 13 kDa secreted protein which is found in high concentrations in biological fluids and is thought to be expressed by all human nucleated cells. Changes in Cystatin C have been documented in a number of cardiovascular diseases, including atherosclerosis, amyloid angiopathy and myocardial infarction. Its low molecular weight also means that Cystatin C can be used as a marker of renal failure.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AD8; cystatin 3; Cystatin-3; Cystatin-C; Cystatin3; CystatinC; MGC117328; OTTHUMP00000030440; OTTHUMP00000164181; OTTHUMP00000164182; OTTMUSP00000016736; RP23-250M11.9
基因别名: Cst3; CysC
UniProt ID: (Mouse) P21460
Entrez Gene ID: (Mouse) 13010
defense response
response to oxidative stress
positive regulation of cell proliferation
negative regulation of peptidase activity
negative regulation of endopeptidase activity
regulation of programmed cell death
extracellular fibril organization
positive regulation of DNA replication
negative regulation of proteolysis
negative regulation of elastin catabolic process
negative regulation of cell death
