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Cystatin C Antibody (PA5-85727) in IHC (P)
Cystatin C Polyclonal Antibody detects Cystatin C protein at cytoplasm in human ovary by immunohistochemical analysis. Sample: Paraffin-embedded human ovary. Cystatin C Polyclonal Antibody (Product # PA5-85727) diluted at 1:400. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
产品信息
PA5-85727
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human Cystatin C.
偶联物
形式
Liquid
浓度
0.56 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2792866
产品详细信息
Keep as concentrated solution.
Predicted reactivity: Rhesus Monkey (96%).
Positive Control: A431, HepG2, Human plasma.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Cystatin C, a member of the type 2 cystatin superfamily, is a potent inhibitor of cysteine proteinases, both endogenous (lysosomal cathepsins), and pathogenic. Cystatin C is a 13 kDa secreted protein which is found in high concentrations in biological fluids and is thought to be expressed by all human nucleated cells. Changes in Cystatin C have been documented in a number of cardiovascular diseases, including atherosclerosis, amyloid angiopathy and myocardial infarction. Its low molecular weight also means that Cystatin C can be used as a marker of renal failure.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AD8; bA218C14.4 (cystatin C); cystatin 3; Cystatin-3; Cystatin-C; Cystatin3; CystatinC; epididymis secretory protein Li 2; Gamma-trace; MGC117328; Neuroendocrine basic polypeptide; OTTHUMP00000030440; OTTHUMP00000164181; OTTHUMP00000164182; OTTMUSP00000016736; Post-gamma-globulin; RP23-250M11.9
基因别名: ARMD11; CST3; HEL-S-2
UniProt ID: (Human) P01034
Entrez Gene ID: (Human) 1471
defense response
negative regulation of peptidase activity
negative regulation of collagen catabolic process
negative regulation of extracellular matrix disassembly
negative regulation of endopeptidase activity
regulation of tissue remodeling
extracellular fibril organization
cellular protein metabolic process
negative regulation of proteolysis
negative regulation of elastin catabolic process
negative regulation of blood vessel remodeling
