Invitrogen

Cytochrome C1 Polyclonal Antibody

Cytochrome C1 Antibody in Immunocytochemistry (ICC/IF)

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Cytochrome C1 Antibody (PA5-51550) in ICC/IF

Immunofluorecent analysis of Cytochrome C1 in human cell line U-251 MG using Cytochrome C1 Polyclonal Antibody (Product # PA5-51550). Staining shows localization to mitochondria.

Cytochrome C1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Cytochrome C1 Antibody in Western Blot (WB)

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产品信息

PA5-51550

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

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免疫组化（石蜡） (IHC (P))

1:200-1:500

免疫细胞化学 (ICC/IF)

0.25-2 µg/mL

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human Cytochrome C1. Recombinant protein control fragment (Product #RP-99401).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2640351

产品详细信息

Immunogen sequence: NSEAARAANN GALPPDLSYI VRARHGGEDY VFSLLTGYCE PPTGVSLREG LYFNPYFPGQ AIAMAPPIYT DVLEFDDGTP ATMSQIAKDV CTFLRWASEP EHDHRKRMGL KMLMMMALLV PLVYTIKRHK WSVLKSRKLA YR

Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.

靶标信息

This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Effects of epigenetic pathway inhibitors on corticotroph tumour AtT20 cells.

Endocrine-related cancer

Lines KE,Filippakopoulos P,Stevenson M,Müller S,Lockstone HE,Wright B,Knapp S,Buck D,Bountra C,Thakker RV

PA5-51550 was used in Western Blot to conclude that JQ1 treatment has anti-proliferative and pro-apoptotic effects on AtT20 cells and reduces ACTH secretion, thereby indicating that BET inhibition may provide a novel approach for treatment of corticotrophinomas.

Sun Mar 01 00:00:00 UTC 2020

Effects of epigenetic pathway inhibitors on corticotroph tumour AtT20 cells.

Endocrine-related cancer

Lines KE,Filippakopoulos P,Stevenson M,Müller S,Lockstone HE,Wright B,Knapp S,Buck D,Bountra C,Thakker RV

Sun Mar 01 00:00:00 UTC 2020

Protective Effects of Foam Rolling against Inflammation and Notexin Induced Muscle Damage in Rats.

International journal of medical sciences

Pablos A,Ceca D,Jorda A,Rivera P,Colmena C,Elvira L,Martínez-Arnau FM,Valles SL

PA5-51550 was used in Western Blot to conclude that applying foam rolling after damage has benefits such as an increase in anti-inflammatory proteins and a reduction of pro-inflammatory proteins, resulting in muscle recovery and better performance.

Mon Oct 05 00:00:00 UTC 2020

Protective Effects of Foam Rolling against Inflammation and Notexin Induced Muscle Damage in Rats.

International journal of medical sciences

Pablos A,Ceca D,Jorda A,Rivera P,Colmena C,Elvira L,Martínez-Arnau FM,Valles SL

Mon Oct 05 00:00:00 UTC 2020

生物信息学

蛋白别名: Complex III subunit 4; Complex III subunit IV; Cytochrome b-c1 complex subunit 4; Cytochrome c-1; Cytochrome c1, heme protein, mitochondrial; Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit

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基因别名: 2610002H19Rik; AA408921; CYC1; MC3DN6; UQCR4

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UniProt ID: (Human) P08574, (Mouse) Q9D0M3

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Entrez Gene ID: (Human) 1537, (Rat) 300047, (Mouse) 66445

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功能

heme binding electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity metal ion binding molecular_function iron ion binding electron carrier activity protein binding

参与通路

response to glucagon mitochondrial electron transport, ubiquinol to cytochrome c transport oxidation-reduction process