Invitrogen

Cytoglobin Polyclonal Antibody

Cytoglobin Antibody in Western Blot (WB)

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Cytoglobin Antibody (PA5-75671) in WB

Western blot analysis of Cytoglobin in Lane 1: HEK293T cell lysate, Lane 2: Raw264.7 cell lysate, Lane 3: PC12 cell lysate. Samples were incubated with Cytoglobin polyclonal antibody (Product # PA5-75671) at a dilution of 1:500.

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产品信息

PA5-75671

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

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产品规格

种属反应

Human, Mouse, Rat

已发表种属

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide corresponding to residues in Human Cytoglobin.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 50% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2719399

产品详细信息

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

靶标信息

Cytoglobin is a ubiquitously expressed hexacoordinate hemoglobin that may facilitate diffusion of oxygen through tissues, scavenge nitric oxide or other reactive oxygen species, or serve a protective function during oxidative stress (Trent and Hargrove, 2002).

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Role of cytoglobin in cigarette smoke constituent-induced loss of nitric oxide bioavailability in vascular smooth muscle cells.

Nitric oxide : biology and chemistry

Mahgoup EM,Khaleel SA,El-Mahdy MA,Abd-Allah AR,Zweier JL

PA5-75671 was used in Western Blot to investigate the effects of cigarette smoke constituents on the rates of NO decay, with focus on the alterations that occur in the process of Cygb-mediated NO metabolism.

Tue Feb 01 00:00:00 UTC 2022

Defining the reducing system of the NO dioxygenase cytoglobin in vascular smooth muscle cells and its critical role in regulating cellular NO decay.

The Journal of biological chemistry

Ilangovan G,Khaleel SA,Kundu T,Hemann C,El-Mahdy MA,Zweier JL

PA5-75671 was used in Western Blotting to investigate the regulation of nitric oxide (NO) metabolism by cytoglobin (Cygb) in vascular smooth muscle cells (SMCs), revealing that Cygb, along with the reducing systems cytochrome b5 (B5)/cytochrome b5 reductase (B5R) and cytochrome P450 reductase (CPR).

Wed Aug 18 00:00:00 UTC 2021

Defining the reducing system of the NO dioxygenase cytoglobin in vascular smooth muscle cells and its critical role in regulating cellular NO decay.

The Journal of biological chemistry

Ilangovan G,Khaleel SA,Kundu T,Hemann C,El-Mahdy MA,Zweier JL

Wed Aug 18 00:00:00 UTC 2021

生物信息学

蛋白别名: Cytoglobin; HGb; Histoglobin; Nitric oxygen dioxygenase; Nitric oxygen dioxygenase CYGB; Nitrite reductase CYGB; NOD; Pseudoperoxidase CYGB; stellate cell activation associated protein; Stellate cell activation-associated protein; Superoxide dismutase CYGB

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基因别名: 3110001K20Rik; CYGB; HGB; Staap; STAP

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UniProt ID: (Human) Q8WWM9, (Mouse) Q9CX80, (Rat) Q921A4

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Entrez Gene ID: (Human) 114757, (Mouse) 114886, (Rat) 170520

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