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Cytohesin 1 Antibody (MA1-060) in ICC/IF
Immunofluorescence analysis of Cytohesin 1 was done on 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with Cytohesin 1 (2E11) Mouse Monoclonal Antibody (Product # MA1-060) at 2 µg/mL in 0.1% BSA and incubated for 3 hours at ro... View More
产品信息
MA1-060
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human,
Mouse
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
2E11
抗原
Purified, His-tagged cytohesin-1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
PEG precipitation
保存液
PBS with 1mg/mL BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2230263
产品详细信息
MA1-060 detects cytohesin-1 from human and mouse cells as well as recombinant human protein.
MA1-060 has been successfully used in Western blot and IF procedures. By Western blot, this antibody detects an ~48 kDa protein representing cytohesin-1.
The MA1-060 immunogen is purified, His-tagged cytohesin-1.
靶标信息
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domains, and thus represents a receptor-type PTP. The similar gene predominately expressed in mouse brain was found to associate with, and thus regulate the activity and cellular localization of MAP kinases. The rat counterpart of this gene was reported to be regulated by the nerve growth factor, which suggested the function of this gene in neuronal growth and differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: CLM1; cytoadhesin 1; Cytohesin-1; FLJ34050; FLJ41900; homolog of secretory protein SEC7; mSec7-1; PH, SEC7 and coiled-coil domain-containing protein 1; pleckstrin homology, Sec7 and coiled-coil domains 1; SEC7 homolog A; SEC7 homolog B2-1
基因别名: B2-1; CLM1; CTH-1; CYTH1; CYTIP; CYTOHESIN-1; D17S811E; mKIAA4240; PSCD1; SEC7
UniProt ID: (Human) Q9P123, (Mouse) Q9QX11
Entrez Gene ID: (Human) 9267, (Mouse) 19157
