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Cytohesin 4 Antibody (PA5-120313) in WB
Western blot analysis of Cytohesin 4 in extracts of various cell lines. Samples were incubated with Cytohesin 4 Polyclonal antibody (Product # PA5-120313) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-120313
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human CYTH4 (NP_037517.1).
偶联物
形式
Liquid
浓度
0.85 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2913885
产品详细信息
Positive test controls include: Mouse liver, Mouse brain, Rat brain. The target is usually found in the following locations: Cell membrane, Peripheral membrane protein.
Immunogen sequence: MDLCHPEPAE LSSGETEELQ RIKWHRKQLL EDIQKLKDEI ADVFAQIDCF ESAEESRMAQ KEKELCIGRK
靶标信息
The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with both ARF1 and ARF5 but is inactive with ARF6. The structures of this gene and CYTH1 are very similar.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cytohesin-4; PH, SEC7 and coiled-coil domain-containing protein 4; pleckstrin homology, Sec7 and coiled/coil domains 4
基因别名: 2510004M07Rik; 5830469K17Rik; AI467541; Cyth4; mFLJ00017; Pscd4; RGD1564842
UniProt ID: (Mouse) Q80YW0
Entrez Gene ID: (Mouse) 72318, (Rat) 500906
