Invitrogen

Cytokeratin 10 Monoclonal Antibody (RKSE60)

Cytokeratin 10 Antibody in Immunohistochemistry (Frozen) (IHC (F))

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Cytokeratin 10 Antibody (MA1-06319) in IHC (F)

Immunohistochemistry on frozen section of swine skin stained with Cytokeratin 10 monoclonal antibody (Product # MA1-06319). Positive staining of the keratinizing layer (higher magnification)

Cytokeratin 10 Antibody in Immunocytochemistry (ICC/IF)

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产品信息

MA1-06319

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:100-1:1,000

免疫组化 (IHC)

查看1篇已发表文章 1篇已发表文章

免疫组化（冰冻） (IHC (F))

1:100-1:200

查看1篇已发表文章 1篇已发表文章

免疫细胞化学 (ICC/IF)

Assay-dependent

查看2篇已发表文章 2篇已发表文章

流式细胞分析 (Flow)

1:100-1:200

产品规格

种属反应

Dog, Human, Mouse, Pig, Rat, Zebrafish

已发表种属

Human, Mouse

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

RKSE60

抗原

Cytokeratins from human epidermal cells.

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

purified

保存液

PBS

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_559753

产品详细信息

MA1-06319 detects cytokeratin 10 in human, canine, rat, porcine, zebrafish and mouse samples.

MA1-06319 has sucessfully been used in Western blotting, flow cytometry, immunocytochemistry, and immunohistochemistry.

The MA1-06319 immmunogens are cytokeratins from the human epidermis.

Store at 4ºC or -20ºC if preferred.

靶标信息

Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (i.e., skin) and non-keratinizing cells (i.e. mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. At least 20 different cytokeratins (CK) in the molecular range of 40-70 kDa and isoelectric points of 5-8. 5 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Monoclonal antibodies to cytokeratin proteins can be useful markers for tumor identification and classification.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Loss of FOXC1 contributes to the corneal epithelial fate switch and pathogenesis.

Signal transduction and targeted therapy

Li M,Zhu L,Liu J,Huang H,Guo H,Wang L,Li L,Gu S,Tan J,Zhong J,Wang B,Mao Z,Fan Y,Liu C,Yuan J,Ouyang H

MA1-06319 was used in Immunocytochemistry to reveal a FOXC1-mediated regulatory network responsible for corneal epithelial homeostasis and provide a potential therapeutic target for corneal ulcer.

Fri Jan 08 00:00:00 UTC 2021

Core transcription regulatory circuitry orchestrates corneal epithelial homeostasis.

Nature communications

Li M,Huang H,Li L,He C,Zhu L,Guo H,Wang L,Liu J,Wu S,Liu J,Xu T,Mao Z,Cao N,Zhang K,Lan F,Ding J,Yuan J,Liu Y,Ouyang H

MA1-06319 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to highlight CRC TF cooperativity for establishment of stem cell identity and lineage commitment, and provides comprehensive regulatory principles for human stratified epithelial homeostasis and pathogenesis.

Mon Jan 18 00:00:00 UTC 2021

Core transcription regulatory circuitry orchestrates corneal epithelial homeostasis.

Nature communications

Li M,Huang H,Li L,He C,Zhu L,Guo H,Wang L,Liu J,Wu S,Liu J,Xu T,Mao Z,Cao N,Zhang K,Lan F,Ding J,Yuan J,Liu Y,Ouyang H

Mon Jan 18 00:00:00 UTC 2021

Epiboly generates the epidermal basal monolayer and spreads the nascent mammalian skin to enclose the embryonic body.

Journal of cell science

Panousopoulou E,Hobbs C,Mason I,Green JB,Formstone CJ

MA1-06319 was used in immunohistochemistry - frozen section to identify factors that regulate epidermal spreading

Sun May 01 00:00:00 UTC 2016

生物信息学

蛋白别名: 56 kDa cytokeratin; CK-10; CK-17; cytokeratin 10; Cytokeratin-10; cytokeratin-17; epidermal keratin 10; epithelial keratin 10; Epithelial keratin-10; intermediate filament protein; K10; keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris); keratin 10, type I; keratin complex 1, acidic, gene 10; Keratin, type I cytoskeletal 10; Keratin, type I cytoskeletal 59 kDa; Keratin-10; keratin-17; krt10 {ECO:0000250|UniProtKB:P13645}; suprabasal cytokeratin 10; Type I keratin Ka10

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基因别名: BCIE; BIE; CK-10; CK10; D130054E02Rik; EHK; K10; K1C1; Ka10; KER10; KPP; Krt-1.10; Krt1-10; KRT10