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NeoBiotechnologies
Cytokeratin 6/KRT6 (Pan; a,b,c) (Basal Cell Marker) Recombinant Rabbit Monoclonal Antibody (rKRT6/9402)
产品信息
3853-MSM14-P1
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG, kappa
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
rKRT6/9402
抗原
Recombinant fragment (around aa400-564) of human KRT6.
偶联物
形式
Liquid
浓度
200 µg/mL
纯化类型
Protein A/G
保存液
PBS with 0.05% BSA
内含物
0.05% sodium azide
保存条件
4° C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Positive Control:Human tonsil or basal cell carcinoma (BCC).
Cellular Location: Cytoplasm.
靶标信息
Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyperproliferative situations. Epidermal injury results in activation of keratinocytes which express CK6 and CK16. CK6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CK-6A; CK-6B; CK-6C; CK-6D; CK-6E; cytokeratin 6A; cytokeratin 6B; cytokeratin 6C; cytokeratin 6D; Cytokeratin-6A; Cytokeratin-6B; Cytokeratin-6C; Cytokeratin-6D; Cytokeratin-6E; K6A; K6B; K6C; kamp-keratin derived antimicrobial peptide; KDAMP; keratin 6A, , type II; keratin 6A, type II; keratin 6B, type II; keratin 6C, type II; keratin 6E; Keratin K6h; keratin, epidermal type II, K6A; keratin, epidermal, type II, K6B; Keratin, type II cytoskeletal 6A; Keratin, type II cytoskeletal 6B; Keratin, type II cytoskeletal 6C; Keratin-6A; Keratin-6B; Keratin-6C; keratin-like 1 (a type II keratin sequence); Type-II keratin Kb10; Type-II keratin Kb12; Type-II keratin Kb6
基因别名: CK-6B; CK-6C; CK-6E; CK6A; CK6B; CK6C; CK6D; K6A; K6B; K6C; K6D; K6E; KRT6A; KRT6B; KRT6C; KRT6D; KRT6E; KRTL1; PC2; PC3; PC4; PPKNEFD
UniProt ID: (Human) P02538, (Human) P04259, (Human) P48668
Entrez Gene ID: (Human) 3853, (Human) 3854, (Human) 286887
