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NeoBiotechnologies
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CK-6B; cytokeratin 6B; Cytokeratin-6B; K6B; keratin 6B, type II; keratin complex 2, basic, gene 6b; keratin, epidermal, type II, K6B; Keratin, type II cytoskeletal 6B; keratin-6-beta; Keratin-6B; keratin-like 1 (a type II keratin sequence); mK6-beta; Type-II keratin Kb10
基因别名: BB144589; CK-6B; CK6B; K6B; Krt2-6b; KRT6B; KRTL1; mK6[b]; PC2; PC4
UniProt ID: (Human) P04259
Entrez Gene ID: (Human) 3854, (Mouse) 16688