Invitrogen

Cytokeratin 8/18 Monoclonal Antibody (5D3)

Cytokeratin 8/18 Antibody in Immunocytochemistry (ICC/IF)

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Cytokeratin 8/18 Antibody (MA5-14088) in ICC/IF

Immunofluorescent analysis of Cytokeratin 8, 18 was performed using 70% confluent log phase MCF-7 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with Cytokeratin 8, 18 (5D3) Mouse Monoclonal Antibody (Product # MA5-14088) at 1:250 dilution in 0.1% BSA and... View More

Cytokeratin 8/18 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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产品信息

MA5-14088

应用

建议稀释比

已发表文章

免疫组化 (IHC)

查看13篇已发表文章 13篇已发表文章

免疫组化（石蜡） (IHC (P))

1:50-1:100

查看2篇已发表文章 2篇已发表文章

免疫细胞化学 (ICC/IF)

1:250

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产品规格

种属反应

Human

已发表种属

Human

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

5D3

抗原

Cytokeratins purified from breast cancer MCF-7 cells

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

Conc. Not Determined

保存液

tissue culture supernatant

内含物

0.09% sodium azide

保存条件

4° C

运输条件

Wet ice

AB_10984885

产品详细信息

MA5-14088 targets Cytokeratin 8/18 in immunohistochemistry (paraffin) applications and shows reactivity with Human samples.

The MA5-14088 immunogen is cytokeratins purified from breast cancer MCF-7 cells.

靶标信息

Keratin 8 belongs to the type B (basic) subfamily of high molecular weight keratins and exists in combination with cytokeratin 18 (type A; acidic subfamily of low molecular weight keratins).

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

A pancreatic adenocarcinoma mimicking hepatoid carcinoma of uncertain histogenesis: A case report and literature review.

Oncology letters

Iliesiu A,Toma RV,Ciongariu AM,Costea R,Zarnescu N,Bîlteanu L

MA5-14088 was used in Immunohistochemistry to provide further knowledge concerning poorly differentiated metastatic adenocarcinoma resembling HC, emphasizing the histopathological and immunohistochemical features of these malignant lesions and raising awareness of the diagnostic difficulties that may arise, as well as the importance of the use immunohistochemistry in differentiating carcinomas of uncertain histogenesis.

Sun Oct 01 00:00:00 UTC 2023

Urinary Tract Tumor Organoids Reveal Eminent Differences in Drug Sensitivities When Compared to 2-Dimensional Culture Systems.

International journal of molecular sciences

Wei Y,Amend B,Todenhöfer T,Lipke N,Aicher WK,Fend F,Stenzl A,Harland N

MA5-14088 was used in Immunohistochemistry to conclude that organoids maintained inter-individual sensitivities towards venetoclax, S63845, and cisplatin.

Sat Jun 04 00:00:00 UTC 2022

A 2-Step Laemmli and Antigen Retrieval Method Improves Immunodetection.

Applied immunohistochemistry & molecular morphology : AIMM

Scalia CR,Gendusa R,Cattoretti G

MA514088 was used in immunohistochemistry - paraffin section to develop an "antigen relaxing" method to improve routine detection of scarce antigens in formalin-fixed, paraffin-embedded material

Fri Jul 01 00:00:00 UTC 2016

A reference image-based method for optimization of clinical immunohistochemistry.

Histopathology

Kap M,Lam KH,Ewing-Graham P,Riegman P

MA5-14088 was used in immunohistochemistry to describe a new method for immunohistochemistry optimization

Sat Aug 01 00:00:00 UTC 2015

Infection of Human Retinal Pigment Epithelium with Chlamydia trachomatis.

PloS one

Boiko E,Maltsev D,Savicheva A,Shalepo K,Khusnutdinova T,Pozniak A,Kvetnoi I,Polyakova V,Suetov A

MA5-14088 was used in immunocytochemistry to research chlamydia trachomatis and infection of human retinal pigment epithelium

Tue Jun 21 00:00:00 UTC 2016

Pancreatic mucinous cystic tumor in Turner syndrome: How a tumor bends to a genetic disease.

International journal of surgery case reports

Pizzi M,Pennelli G,Merante-Boschin I,Fassan M,Pelizzo MR,Rugge M

MA5-14088 was used in immunohistochemistry to report on a case of pancreatic mucinous cystic tumor in a patient with Turner syndrome

Fri Nov 08 00:00:00 UTC 2013

CD49f-based selection of circulating tumor cells (CTCs) improves detection across breast cancer subtypes.

Cancer letters

Mostert B,Kraan J,Sieuwerts AM,van der Spoel P,Bolt-de Vries J,Prager-van der Smissen WJ,Smid M,Timmermans AM,Martens JW,Gratama JW,Foekens JA,Sleijfer S

MA5-14088 was used in immunohistochemistry to investigate the utility of cell markers for detecting circulating tumor cells

Fri Jun 01 00:00:00 UTC 2012

Primary intracranial Ewing sarcoma with an unusually aggressive course: a case report and review of the literature.

Neuropathology : official journal of the Japanese Society of Neuropathology

Tanboon J,Sitthinamsuwan B,Paruang T,Marrano P,Thorner PS

MA5-14088 was used in immunohistochemistry to report on a case of primary intracranial Ewing sarcoma with an unusually aggressive course

Fri Jun 01 00:00:00 UTC 2012

Sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression: report of a case and literature review.

Diagnostic pathology

Yin WH,Li J,Chan JK

MA5-14088 was used in immunohistochemistry to report on a case of sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression

Thu Apr 12 00:00:00 UTC 2012

Histological assessment of PAXgene tissue fixation and stabilization reagents.

PloS one

Kap M,Smedts F,Oosterhuis W,Winther R,Christensen N,Reischauer B,Viertler C,Groelz D,Becker KF,Zatloukal K,Langer R,Slotta-Huspenina J,Bodo K,de Jong B,Oelmuller U,Riegman P

MA5-14088 was used in immunohistochemistry - paraffin section to examine the suitability of PAXgene tissue fixation for (immuno)histological methods

Mon Mar 26 00:00:00 UTC 2012

Primary sellar neuroblastoma presenting with syndrome of inappropriate secretion of anti-diuretic hormone.

Endocrine pathology

Radotra B,Apostolopoulos V,Sandison A,Hatfield EC,Mendoza N,Moss J,Mehta A,Glaser M,Meeran K,Roncaroli F

MA5-14088 was used in immunohistochemistry to investigate the secretion of anti-diuretic hormone in neuroblastoma

Wed Dec 01 00:00:00 UTC 2010

Isolation and culture of adult human liver progenitor cells: in vitro differentiation to hepatocyte-like cells.

Methods in molecular biology (Clifton, N.J.)

Gerbal-Chaloin S,Duret C,Raulet E,Navarro F,Blanc P,Ramos J,Maurel P,Daujat-Chavanieu M

MA5-14088 was used in immunohistochemistry to investigate the culture and differentiation of human liver progenitor cells

Thu Oct 28 00:00:00 UTC 2010

Parietal epithelia cells in the urine as a marker of disease activity in glomerular diseases.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

Achenbach J,Mengel M,Tossidou I,Peters I,Park JK,Haubitz M,Ehrich JH,Haller H,Schiffer M

MA5-14088 was used in immunocytochemistry to evaluate the presence of PDX-positive cells in urine as a marker for glomerular diseases

Wed Oct 01 00:00:00 UTC 2008

Isolation, characterization, and differentiation to hepatocyte-like cells of nonparenchymal epithelial cells from adult human liver.

Stem cells (Dayton, Ohio)

Duret C,Gerbal-Chaloin S,Ramos J,Fabre JM,Jacquet E,Navarro F,Blanc P,Sa-Cunha A,Maurel P,Daujat-Chavanieu M

MA5-14088 was used in immunocytochemistry to characterize nonparenchymal epithelial cells from adult human liver

Sun Jul 01 00:00:00 UTC 2007

An immunohistochemical profile of giant cell carcinoma of the larynx.

Auris, nasus, larynx

Gurbuz Y,Kose N,Aydin O,Ozturk M

MA5-14088 was used in immunohistochemistry to report on a case of giant cell carcinoma of the larynx

Sat Sep 01 00:00:00 UTC 2007

An unusual presentation of Helicobacter pylori infection: so-called "Russell body gastritis".

Virchows Archiv : an international journal of pathology

Ensari A,Savas B,Okcu Heper A,Kuzu I,Idilman R

MA5-14088 was used in immunohistochemistry to report on a case of Helicobacter pylori infection with Russell body involvement

Fri Apr 01 00:00:00 UTC 2005

Breast cancer in an MSH2 gene mutation carrier.

Human pathology

Westenend PJ,Schütte R,Hoogmans MM,Wagner A,Dinjens WN

MA5-14088 was used in immunohistochemistry to report on a case of breast cancer in a MSH2 gene mutation carrier

Thu Dec 01 00:00:00 UTC 2005

Cytokeratin expression in lichen amyloidosus and macular amyloidosis.

Journal of the European Academy of Dermatology and Venereology : JEADV

Apaydin R,Gürbüz Y,Bayramgürler D,Müezzinoglu B,Bilen N

MA5-14088 was used in immunohistochemistry to investigate the expression of cytokeratins in lichen and macular amyloidosis and their diagnostic value

Sat May 01 00:00:00 UTC 2004

生物信息学

蛋白别名: Cell proliferation-inducing gene 46 protein; CK-18; CK-8; cytokeratin 18; Cytokeratin-18; Cytokeratin-8; K18; K8; keratin 18, type I; keratin 8, type II; Keratin, type I cytoskeletal 18; Keratin, type II cytoskeletal 8; Keratin-18; Keratin-8; Type-II keratin Kb8

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基因别名: CARD2; CK-18; CK-8; CK8; CYK18; CYK8; K18; K2C8; K8; KO; KRT18; KRT8; PIG46

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UniProt ID: (Human) P05783, (Human) P05787

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Entrez Gene ID: (Human) 3875, (Human) 3856

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功能

structural molecule activity protein binding poly(A) RNA binding scaffold protein binding cadherin binding involved in cell-cell adhesion protein complex binding

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