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产品信息
18-0213
产品规格
种属反应
Human
宿主/亚型
Mouse
分类
Monoclonal
类型
Antibody
克隆号
Zym5.2 (UCD/PR.10-11)
抗原
Human keratin 8 & 18
偶联物
形式
Liquid
浓度
0.34443 mg/mL
纯化类型
purified
保存液
PBS with 1% BSA
内含物
0.1% sodium azide
保存条件
2-8°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2925240
产品详细信息
This monoclonal antibody reacts with human cytokeratins 8 and 18, low molecular weight cytokeratins found in simple epithelium and secretory epithelium. Clone Zym5.2 will react with adenocarcinoma, mesothelioma, and carcinoma derived from simple epithelia, but will not react with stratified squamous epithelia. Positive tissue: Normal colon.
Clone/PAD: Zym5.2 (UCD/PR.10-11)
Immunogen: Human keratin 8 & 18
Specificity: Cytokeratin 8 (52.5 kDa) and 18 (45 kDa)
Expected Staining Pattern: Cytoplasmic and membrane
靶标信息
Keratin 8 belongs to the type B (basic) subfamily of high molecular weight keratins and exists in combination with cytokeratin 18 (type A; acidic subfamily of low molecular weight keratins).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cell proliferation-inducing gene 46 protein; CK-18; CK-8; cytokeratin 18; Cytokeratin-18; Cytokeratin-8; K18; K8; keratin 18, type I; keratin 8, type II; Keratin, type I cytoskeletal 18; Keratin, type II cytoskeletal 8; Keratin-18; Keratin-8; Type-II keratin Kb8
基因别名: CARD2; CK-18; CK-8; CK8; CYK18; CYK8; K18; K2C8; K8; KO; KRT18; KRT8; PIG46
UniProt ID: (Human) P05783, (Human) P05787
Entrez Gene ID: (Human) 3875, (Human) 3856
cell cycle
anatomical structure morphogenesis
viral process
tumor necrosis factor-mediated signaling pathway
Golgi to plasma membrane CFTR protein transport
negative regulation of apoptotic process
intermediate filament cytoskeleton organization
extrinsic apoptotic signaling pathway
hepatocyte apoptotic process
cell-cell adhesion
sarcomere organization
response to hydrostatic pressure
response to other organism
cell differentiation involved in embryonic placenta development
