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产品信息
3856-MSM6-P0
应用
建议稀释比
已发表文章
产品规格
种属反应
Bovine,
Human,
Sheep,
Pig,
Rabbit
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
C-43
抗原
Cytoskeletal preparation from HeLa cells
偶联物
形式
Liquid
浓度
200 µg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4, with 0.05% BSA
内含物
0.05% sodium azide
保存条件
4° C, do not freeze
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Does not react with Mouse, Rat, Chicken or Xenopus laevis
靶标信息
Cytokeratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. Cutokeratin 8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CK-8; cytokeratin 8; Cytokeratin-8; Cytokeratin-A; K8; KERA; keratin 8, type II; Keratin, type II cytoskeletal 8; Keratin-8; type II cytokeratin A (no.8); Type-II keratin Kb8
基因别名: CARD2; CK-8; CK8; CYK8; K2C8; K8; KO; KRT2-8; KRT8
UniProt ID: (Bovine) P05786, (Human) P05787
Entrez Gene ID: (Rabbit) 100348891, (Bovine) 281269, (Pig) 100152077, (Human) 3856, (Sheep) 101110495
