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产品信息
3856-MSM1-P1ABX
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat,
Zebrafish
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
H1
抗原
Cytoskeleton preparation containing cytokeratin 8
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Cytokeratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. Cutokeratin 8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CK-8; Cytokeratin endo A; Cytokeratin-8; etID33550.23; etID43142.23; etID43142.8; K8; keratin 8, type II; keratin complex 2, basic, gene 8; keratin, type 2, gene 8; Keratin, type II cytoskeletal 8; Keratin-8; Type-II keratin Kb8
基因别名: CARD2; cb186; CK-8; CK8; CYK8; CYKER; DreK8; K2C8; K8; KO; Krt2-8; KRT8; sb:cb186; wu:fa20h05; wu:fa95h10; wu:fb96c06; zf-K8; zfk8
UniProt ID: (Human) P05787, (Rat) Q10758, (Zebrafish) Q6NWF6
Entrez Gene ID: (Human) 3856, (Rat) 25626, (Zebrafish) 797433
