NeoBiotechnologies

Cytokeratin, Type I (Epithelial Marker) Recombinant Rabbit Monoclonal Antibody (KRTL/4440R)

Cytokeratin, Type I (Epithelial Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 4

Cytokeratin, Type I (Epithelial Marker) Antibody (RBM42-4440-P0) in IHC (P)

Formalin-fixed, paraffin-embedded human colon carcinoma stained with CK Type I Recombinant Rabbit Monoclonal Antibody (KRTL/4440R).

Cytokeratin, Type I (Epithelial Marker) Antibody in SDS-PAGE (SDS-PAGE)

Product Image Gallery

产品信息

RBM42-4440-P0

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

Assay-dependent

免疫组织化学（多聚甲醛固定） (IHC (PFA))

1-2 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

KRTL/4440R

抗原

Synthetic peptide corresponding to Type I Cytokeratins residues within aa100-200 of Type I Cytokeratins

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

200 µg/mL

纯化类型

Protein A/G

保存液

PBS, pH 7.4, with 0.05% BSA

内含物

0.05% sodium azide

保存条件

4° C, do not freeze

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

Cytokeratin pan is part of a subfamily of intermediate filament proteins that are characterized by remarkable biochemical diversity, and represented in human epithelial tissues by at least 20 different polypeptides. Cytokeratins range in molecular weight between 40 kDa- 68 kDa, and an isoelectric pH between 4.9-7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays. The composition of cytokeratin pairs vary with the epithelial cell type, stage of differentiation, cellular growth environment, and disease state. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。

引用该产品

生物信息学

蛋白别名: 40-kDa keratin intermediate filament; Acidic Cytokeratin; Cell proliferation-inducing gene 46 protein; CK-10; CK-14; CK-15; CK-16; CK-18; CK-19; CK-9; cytokeratin 10; cytokeratin 14; cytokeratin 15; cytokeratin 16; cytokeratin 18; cytokeratin 19; cytokeratin 9; Cytokeratin-10; Cytokeratin-14; Cytokeratin-15; Cytokeratin-16; Cytokeratin-18; Cytokeratin-19; Cytokeratin-9; focal non-epidermolytic palmoplantar keratoderma; HMWCK; K10; K14; K15; K16; K18; K19; K9; keratin 10, type I; keratin 14, type I; keratin 15, type I; keratin 16, type I; keratin 18, type I; keratin 19, type I; keratin 9, type I; Keratin, type I cytoskeletal 10; Keratin, type I cytoskeletal 14; Keratin, type I cytoskeletal 15; Keratin, type I cytoskeletal 16; Keratin, type I cytoskeletal 18; Keratin, type I cytoskeletal 19; Keratin, type I cytoskeletal 9; keratin, type I, 40-kd; Keratin-10; Keratin-14; Keratin-15; keratin-15, basic; keratin-15, beta; Keratin-16; Keratin-18; Keratin-19; Keratin-9; pan keratin; pankeratin; type I cytoskeletal 15; type I cytoskeletal 9

查看更多收起

基因别名: BCIE; BIE; CK-18; CK-9; CK10; CK14; CK15; CK16; CK19; CYK18; EBS3; EBS4; EHK; EPPK; FNEPPK; K10; K14; K15; K16; K18; K19; K1CO; K1CP; K1CS; K9; KPP; KRT10; KRT14; KRT15; KRT16; KRT16A; KRT18; KRT19; KRT9; KRTB; NEPPK; NFJ; PC1; PIG46