Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 4
DBC1 Antibody (PA5-121069) in IHC (P)
Immunohistochemistry analysis of DBC1 in paraffin-embedded human rectal cancer. Samples were incubated with DBC1 Polyclonal antibody (Product # PA5-121069) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-121069
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 654-923 of human CCAR2 (NP_066997.3).
偶联物
形式
Liquid
浓度
0.48 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2914641
产品详细信息
Positive test controls include: Jurkat, HeLa, Rat lung. The target is usually found in the following locations: Cytoplasm, Nucleus.
Immunogen sequence: LLRDDGEEEF AGAKLEDSEV RSVASNQSEM EFSSLQDMPK ELDPSAVLPL DCLLAFVFFD ANWCGYLHRR DLERILLTLG IRLSAEQAKQ LVSRVVTQNI CQYRSLQYSR QEGLDGGLPE EVLFGNLDLL PPPGKSTKPG AAPTEHKALV SHNGSLINVG SLLQRAEQQD SGRLYLENKI HTLELKLEES HNRFSATEVT NKTLAAEMQE LRVRLAEAEE TARTAERQKS QLQRLLQELR RRLTPLQLEI QRVVEKADSW VEKEEPAPSN
靶标信息
DBC1 is located within a chromosomal region that shows loss of heterozygosity in some bladder cancers. It contains a 5' CpG island that may be a frequent target of hypermethylation, and it may undergo hypermethylation-based silencing in some bladder cancers.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Cell cycle and apoptosis regulator protein 2; Cell division cycle and apoptosis regulator protein 2; DBC-1; DBC.1; DBCCR1; DBIRD complex subunit KIAA1967; deleted in breast cancer 1; Deleted in breast cancer gene 1 protein; FAM5A; NET35; p30 DBC; p30 DBC protein
基因别名: 2610301G19Rik; CCAR2; DBC-1; DBC1; KIAA1967; mKIAA1967; NET35; p30 DBC; p30DBC; RGD1309922
UniProt ID: (Human) Q8N8M1, (Mouse) Q8VDP4
Entrez Gene ID: (Human) 57805, (Mouse) 219158, (Rat) 306007
transcription, DNA-templated
mRNA processing
cellular response to DNA damage stimulus
cell cycle
RNA splicing
response to UV
Wnt signaling pathway
negative regulation of cell growth
regulation of protein stability
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
regulation of DNA-templated transcription, elongation
regulation of circadian rhythm
positive regulation of apoptotic process
negative regulation of catalytic activity
mitochondrial fragmentation involved in apoptotic process
negative regulation of transcription, DNA-templated
rhythmic process
positive regulation of canonical Wnt signaling pathway
regulation of protein deacetylation
regulation of cellular response to heat
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
positive regulation of DNA damage checkpoint
regulation of transcription, DNA-templated
apoptotic process
