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DCT Antibody (PA5-36485) in WB
Antibiotics (Basel, Switzerland) 2023 -
Effect of the isolated compounds from S. taxoides on the melanogenic protein expression in B16-F1 cells. Cells were treated with 25 ug/mL ( A ) and 50 ug/mL ( B ) of the isolated compounds. Whole cell lysates were subjected to Western blot analysis using specific antibodies against MITF, tyrosinase, TRP1 and TRP2.
产品信息
PA5-36485
产品规格
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 50-100 of human TRP2
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2553545
产品详细信息
This antibody detects endogenous protein at a molecular weight of 60 kDa.
Purity is >95% by SDS-PAGE.
靶标信息
The TYR-related proteins, TRP1 and TRP2, are also specifically expressed in melanocytes, and they likewise contribute to the synthesis of melanin within the melanosomes. The TRPs, including TYR, all share a similar transmembrane region, contain two metal-binding regions and a cysteinerich epidermal growth factor motif, and are localized in the melanosomal membrane. These proteins, however, have distinct catalytic activity, and they individually contribute to the biosynthesis of melanin biopolymers. The TRPs are believed to exist as a multi-enzyme complex, as these proteins form aggregates together, and the expression of TRP1 also helps stabilize TYR in melanocytes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
