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Sequence of this protein is as follows: RTAENKLDTK YPYVCHAELN AIMNKNSTDV KGCSMYVALF PCNECAKLII QAGIKEVIFM SDKYHDSDEA TAARLLFNMA GVTFRKFIPK CSKIVIDFDS INSRPSQKLQ
The protein encoded by this gene catalyzes the deamination of dCMP to dUMP, the nucleotide substrate for thymidylate synthase. The encoded protein is allosterically activated by dCTP and inhibited by dTTP, and is found as a homohexamer. This protein uses zinc as a cofactor for its activity. Two transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: dCMP deaminase; Deoxycytidylate deaminase
基因别名: DCTD
UniProt ID: (Human) P32321
Entrez Gene ID: (Human) 1635