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Recommended positive controls: A549, HeLa, HepG2, HCT116.
Predicted reactivity: Mouse (94%), Rat (94%), Xenopus laevis (89%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Potently stimulates the neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes from the NEDD8-conjugating E2 enzyme UBC12. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. [UniProt]
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DCN1, defective in cullin neddylation 1, domain containing 2; DCN1-like protein 2; DCNL2; DCUN1 domain-containing protein 2; Defective in cullin neddylation protein 1-like protein 2
基因别名: C13orf17; DCUN1D2; DCUN1L2
UniProt ID: (Human) Q6PH85
Entrez Gene ID: (Human) 55208