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Immunogen sequence: QFMACTQAGE RTAIYCLTQN EWRLDEATDS FFQNPDSLHR ESMRNAVDKK KLERLYGRY
Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 80%.
Potently stimulates the neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes from the NEDD8-conjugating E2 enzyme UBC12. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DCN1, defective in cullin neddylation 1, domain containing 2; DCN1-like protein 2; DCNL2; DCUN1 domain-containing protein 2; Defective in cullin neddylation protein 1-like protein 2
Gene Aliases: C13orf17; DCUN1D2; DCUN1L2
UniProt ID: (Human) Q6PH85
Entrez Gene ID: (Human) 55208
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