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DDOST Antibody (PA5-97181) in WB
Western blot analysis of DDOST in extracts of various cell lines. Samples were incubated with DDOST Polyclonal antibody (Product # PA5-97181) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
产品信息
PA5-97181
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human DDOST (NP_0052072)
偶联物
形式
Liquid
浓度
2.88 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2808983
产品详细信息
Immunogen sequence: VCASGPRTLV LLDNLNVRET HSLFFRSLKD RGFELTFKTA DDPSLSLIKY GEFLYDNLII FSPSVEDFGG NINVETISAF IDGGGSVLVA ASSDIGDPLR ELGSECGIEF DEEKTAVIDH HNYDISDLGQ HTLIVADTEN LLKAPTIVGK SSLNPILFRG VGMVADPDNP LVLDILTGSS TSYSFFPDKP ITQYPHAVGK NTLLIAGLQA RNNARVIFSG SLDFFSDSFF NSAVQKAAPG SQRYSQTGNY ELAVALSRWV F; Positive Samples: U-87MG, HT-29, HepG2, A-549, Mouse kidney, Mouse liver, Mouse brain, Rat testis; Cellular Location: Endoplasmic reticulum membrane, Single-pass type I membrane protein
靶标信息
This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation end products (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: advanced glycation end-product receptor 1; advanced glycation endproduct receptor 1; AGE-R1; DDOST 48 kDa subunit; dolichyl-di-phosphooligosaccharide-protein glycotransferase; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic); dolichyl-diphosphooligosaccharide-protein glycotransferase; MGC2191; oligosaccharyl transferase 48 kDa subunit; oligosaccharyltransferase 48 kDa subunit; oligosaccharyltransferase subunit 48
基因别名: AGER1; CDG1R; DDOST; KIAA0115; OK/SW-cl.45; OKSWcl45; OST; OST48; WBP1
UniProt ID: (Human) P39656, (Mouse) O54734, (Rat) Q641Y0
Entrez Gene ID: (Human) 1650, (Mouse) 13200, (Rat) 313648
