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产品信息
PA5-22050
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Hamster
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 70 and 346 of DDX3 (Uniprot ID#O15523)
偶联物
形式
Liquid
浓度
0.89 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11152407
产品详细信息
Recommended positive controls: H1299, HepG2, mouse brain, rat testis, Jurkat, Raji, NCI-H929.
Predicted reactivity: Mouse (95%), Rat (94%), Rhesus Monkey (99%), Chimpanzee (97%), Bovine (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. DDX3Y is one member of DEAD box RNA helicases, encode by the gene locate on the chromosome Y in the azoospermia factor A region.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: ATP-dependent RNA helicase DDX3Y; D1Pas1 related sequence 1; D1Pas1-related sequence 1; DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked; DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked; DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide, Y chromosome; DEAD box protein 3, Y-chromosomal; DEAD-box RNA helicase DEAD2; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide, Y chromosome; mDEAD2; uncharacterized protein LOC364073
基因别名: 8030469F12Rik; D1Pas1-rs1; DBY; DDX3Y; Dead2; RGD1309586
UniProt ID: (Human) O15523, (Mouse) Q62095
Entrez Gene ID: (Human) 8653, (Rat) 364073, (Mouse) 26900
DNA binding
RNA binding
ATP-dependent RNA helicase activity
ATP binding
nucleic acid binding
GTPase activity
ATP-dependent DNA helicase activity
helicase activity
transcription factor binding
poly(A) binding
eukaryotic initiation factor 4E binding
ATPase activity
nucleoside-triphosphatase activity
translation initiation factor binding
RNA stem-loop binding
ribosomal small subunit binding
CTPase activity
poly(A) RNA binding
mRNA 5'-UTR binding
nucleotide binding
hydrolase activity
chromosome segregation
metabolic process
extrinsic apoptotic signaling pathway via death domain receptors
response to virus
RNA secondary structure unwinding
positive regulation of gene expression
negative regulation of translation
positive regulation of cell growth
negative regulation of cell growth
negative regulation of protein complex assembly
DNA duplex unwinding
stress granule assembly
intracellular signal transduction
mature ribosome assembly
positive regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of viral genome replication
innate immune response
positive regulation of translation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of translational initiation
cellular response to arsenic-containing substance
cellular response to osmotic stress
intrinsic apoptotic signaling pathway
positive regulation of G1/S transition of mitotic cell cycle
negative regulation of intrinsic apoptotic signaling pathway
translational initiation
regulation of gene expression
