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Immunogen sequence: VDTKLNEQLK TSFFLVREDT KAAVLLHLLH NVVRPQDQTV VFVATKHHAE YLTELLTTQR VSCAHIYSAL DPTARKINLA KFTLGKCSTL IVTDLAARGL DIPLLDNVIN YSFP
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 91%.
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The nucleolar protein encoded by this gene interacts in a hormone-dependent manner with nuclear receptors, and represses their transcriptional activity. Alternative splice variants that encode different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 5-Apr; ATP-dependent RNA helicase DDX54; ATP-dependent RNA helicase DP97; DEAD (Asp-Glu-Ala-Asp) box polypeptide 54; DEAD box helicase 97 KDa; DEAD box protein 54; DEAD box RNA helicase 97 kDa
基因别名: DDX54; DP97
UniProt ID: (Human) Q8TDD1
Entrez Gene ID: (Human) 79039