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DECR2 Antibody (PA5-120571) in WB
Western blot analysis of DECR2 in extracts of various cell lines. Samples were incubated with DECR2 Polyclonal antibody (Product # PA5-120571) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3s.
产品信息
PA5-120571
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 140-240 of human DECR2 (NP_065715.1).
偶联物
形式
Liquid
浓度
1.48 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2914143
产品详细信息
Positive test controls include: HeLa, Mouse liver, Rat liver, Rat kidney.
Immunogen sequence: GTFNVSRVLY EKFFRDHGGV IVNITATLGN RGQALQVHAG SAKAAVDAMT RHLAVEWGPQ NIRVNSLAPG PISGTEGLRR LGGPQASLST KVTASPLQRL G
靶标信息
DECR2 (2, 4-dienoyl-CoA reductase 2), also known as PDCR (peroxisomal 2, 4-dienoyl-CoA reductase) or SDR17C1, is a 292 amino acid member of the short-chain dehydrogenases/reductases (SDR) protein family and the 2, 4-dienoyl-CoA reductase protein subfamily. Localized to the peroxisome, DECR2 is an auxiliary enzyme of beta-oxidation that catalyzes the NADP-dependent reduction of 2, 4-dienoyl-CoA to yield trans-3-enoyl-CoA. DECR2 has also been shown to have catalytic activity towards 2, 4, 7, 10, 13, 16, 19-docosaheptaenoyl-CoA and short and medium chain 2, 4-dienoyl-CoAs, suggesting that DECR2 is not a rate limiting step in the degradation of docosahexaenoic acid in the peroxisome. DECR2 is expressed as three isoforms produced by alternative splicing events.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 2,4-dienoyl CoA reductase 2, peroxisomal; 2,4-dienoyl-CoA reductase 2; 2-4-dienoyl-Coenzyme A reductase 2, peroxisomal; DCR-AKL; pDCR; peroxisomal 2,4-dienoyl-CoA reductase; Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]; putative peroxisomal 2,4-dienoyl-CoA reductase; putative peroxisomal 24-dienoyl-CoA reductase; pVI-AKL; Short chain dehydrogenase/reductase family 17C member 1; short chain dehydrogenase/reductase family 17C, member 1
基因别名: Dcrakl; DECR2; PDCR; putativeperoxisomal24-dienoyl-CoAreductase; SDR17C1
UniProt ID: (Human) Q9NUI1, (Mouse) Q9WV68, (Rat) Q9Z2M4
Entrez Gene ID: (Human) 26063, (Mouse) 26378, (Rat) 64461
