Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 1
DEGS1 Antibody (PA5-88680) in WB
Western blot analysis of DEGS1 in extracts of various cell lines. Samples were incubated with DEGS1 Polyclonal antibody (Product # PA5-88680) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
产品信息
PA5-88680
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 234-323 of human DEGS1 (NP_0036671)
偶联物
形式
Liquid
浓度
0.19 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2805071
产品详细信息
Immunogen sequence: YMFLKGHETY SYYGPLNLLT FNVGYHNEHH DFPNIPGKSL PLVRKIAAEY YDNLPHYNSW IKVLYDFVMD DTISPYSRMK RHQKGEMVLE; Positive Samples: HeLa, A-549, 293T; Cellular Location: Endoplasmic reticulum membrane, Lipid-anchor, Membrane, Mitochondrion, Multi-pass membrane protein
靶标信息
The product of the DEGS1 gene is a member of the membrane fatty acid (sphingolipid delta 4 ) desaturase family. Reported to function by inserting double bonds at delta 4 position in fatty acids. DEGS1 is an intracellular enzyme. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulation biosynthetic processing of the EGF receptor. Two splice variants have been identified.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Cell migration-inducing gene 15 protein; Degenerative spermatocyte homolog 1; degenerative spermatocyte homolog 1, lipid desaturase; degenerative spermatocyte homolog, lipid desaturase; Delta(4)-desaturase; delta(4)-desaturase, sphingolipid 1; dihydroceramide desaturase 1; Dihydroceramide desaturase-1; DSH1; membrane fatty acid (lipid) desaturase; Membrane lipid desaturase; MGC5079; migration-inducing gene 15 protein; Retinol isomerase; sphingolipid 1; sphingolipid delta 4 desaturase; sphingolipid delta(4)-desaturase 1; Sphingolipid delta(4)-desaturase DES1
基因别名: DEGS; DEGS-1; DEGS1; Des-1; DES1; FADS7; MIG15; MLD
UniProt ID: (Human) O15121
Entrez Gene ID: (Human) 8560
