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Peptide sequence: FFFNMLFVFR YCRMLEEGSF RGRTADFVFM FLFGGVLMTL LGLLGSLFFL
Sequence homology: Cow: 100%; Dog: 100%; Goat: 92%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
The protein encoded by this gene belongs to the derlin family, and resides in the endoplasmic reticulum (ER). Proteins that are unfolded or misfolded in the ER must be refolded or degraded to maintain the homeostasis of the ER. This protein appears to be involved in the degradation of misfolded glycoproteins in the ER. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Degradation in endoplasmic reticulum protein 3; Der1-like domain family, member 3; Der1-like protein 3; Derlin-3; DERtrin 3; DERtrin-3; MGC71803
基因别名: C22orf14; DER3; DERL3; derlin-3; IZP6; LLN2
UniProt ID: (Human) Q96Q80
Entrez Gene ID: (Human) 91319