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DGAT1 Antibody (PA5-18634) in ICC/IF
Immunocytochemistry analysis of DGAT1 using DGAT1 Polyclonal Antibody (Product # PA5-18634) in paraformaldehyde fixed A431 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (2 µg/mL), showing endoplasmic reticulum and cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (2 µg/mL).
产品信息
PA5-18634
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (QNSMKPFKDMDYS) corresponding to the internal amino acids of DGAT1 (aa 305-317).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_10987018
产品详细信息
This antibody is predicted to react with canine and mouse based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.
靶标信息
The enzyme encoded by this gene utilizes diacylglycerol and fatty acyl CoA as substrates in order to catalyze the final stage of triacylglycerol synthesis. It is also involved in cellular as well as physiological metabolic processes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ACAT related gene product 1; ACAT-related gene product 1; Acyl coenzyme A; acyl coenzyme A:cholesterol acyltransferase related gene 1; Acyl-CoA retinol O-fatty-acyltransferase; acyl-CoA:diacylglycerol acyltransferase; ARAT; diacylglycerol acyltransferase 1; Diacylglycerol O-acyltransferase 1; Diglyceride acyltransferase; EC 2.3.1.20; retinol O-fatty-acyltransferase
基因别名: AGRP1; ARAT; ARGP1; C75990; D15Ertd23e; DGAT; DGAT1; DIAR7
UniProt ID: (Human) O75907, (Mouse) Q9Z2A7
Entrez Gene ID: (Human) 8694, (Mouse) 13350
triglyceride metabolic process
triglyceride biosynthetic process
lipid storage
very-low-density lipoprotein particle assembly
long-chain fatty-acyl-CoA metabolic process
acylglycerol acyl-chain remodeling
retinol metabolic process
diacylglycerol metabolic process
fatty acid homeostasis
insulin secretion
glycerolipid metabolic process
