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Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Binds its own mRNA and that of DHFR.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Dihydrofolate reductase 2, mitochondrial; dihydrofolate reductase like 1; dihydrofolate reductase pseudogene 4; Dihydrofolate reductase, mitochondrial; dihydrofolate reductase-like 1; Dihydrofolate reductase-like protein 1
基因别名: DHFR2; DHFRL1; DHFRP4
UniProt ID: (Human) Q86XF0
Entrez Gene ID: (Human) 200895