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DHODH Antibody (PA5-79153) in IHC (P)
Immunohistochemistry analysis of DHODH on paraffin-embedded human lung cancer tissue. Sample was incubated with DHODH polyclonal antibody (Product# PA5-79153) with a dilution of 1 µg/mL, and developed by Streptavidin-Biotin-Complex (SABC) with DAB chromogen method.
Product Details
PA5-79153
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human DHODH (132-173aa RVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAKLTE D).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2746269
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human Hela whole cell, human A431 whole cell, human HepG2 whole cell, human MCF-7 whole cell, rat testis tissue, rat liver tissue, mouse testis tissue, mouse liver tissue. IHC: mouse intestine tissue, rat intestine tissue, human lung cancer tissue.
Target Information
The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane. [provided by RefSeq, Jul 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DHOdehase; Dihydroorotate dehydrogenase (quinone), mitochondrial; dihydroorotate dehydrogenase, mitochondrial; Dihydroorotate oxidase; human complement of yeast URA1
Gene Aliases: 2810417D19Rik; AI834883; DHOdehase; DHODH; POADS; URA1
UniProt ID: (Human) Q02127, (Rat) Q63707, (Mouse) O35435
Entrez Gene ID: (Human) 1723, (Rat) 65156, (Mouse) 56749
'de novo' pyrimidine nucleobase biosynthetic process
female pregnancy
lactation
response to organic cyclic compound
response to caffeine
response to drug
response to starvation
positive regulation of apoptotic process
'de novo' UMP biosynthetic process
oxidation-reduction process
regulation of mitochondrial fission
pyrimidine nucleotide biosynthetic process
UMP biosynthetic process
pyrimidine nucleoside biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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